Papers/PMID:29916550
Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice.
Molecular medicine reports2018The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
(-)-epigallocatechin 3-gallate — decreases tumour necrosis factor alpha concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“After treatment with EGCG, IL-2 and IFN-γ levels were significantly increased (P<0.05 vs. asthma group); IL-4, IL-6 and TNF-α levels were significantly diminished (P<0.05 vs. asthma group).”
Quoted verbatim from Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice.. - Study
- animal · not in humans
- Duration
- 7 days
- Dose
- 10 or 20 mg/kg/day EGCG by caudal vein injection; the sentence does not say which EGCG group
- Population
- Male Balb/c mice with ovalbumin-induced asthma, serum cytokines by cytometric bead array, EGCG-treated groups versus untreated asthma model group
Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice.2018PMID:29916550Permalink
(-)-epigallocatechin 3-gallate — decreases interleukin-6 concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“After treatment with EGCG, IL-2 and IFN-γ levels were significantly increased (P<0.05 vs. asthma group); IL-4, IL-6 and TNF-α levels were significantly diminished (P<0.05 vs. asthma group).”
Quoted verbatim from Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice.. - Study
- animal · not in humans
- Duration
- 7 days
- Dose
- 10 or 20 mg/kg/day EGCG by caudal vein injection; the sentence does not say which EGCG group
- Population
- Male Balb/c mice with ovalbumin-induced asthma, serum cytokines by cytometric bead array, EGCG-treated groups versus untreated asthma model group
Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice.2018PMID:29916550Permalink