Papers/PMID:29480324
Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers.
European journal of clinical pharmacology2018The record
1 finding drawn from this paper, on 1 compound across 1 endpoint.
What it reported
How to read these marksWhat moved
1 finding
(-)-epigallocatechin 3-gallate — inhibits SLCO1A2
SpeculativeGrade F, Speculative. Mechanistic inference, or no evidence found.Finding“EGCG competitively inhibited OATP1A2-mediated uptake of sulphobromophthalein and nadolol with Ki values of 21.6 and 19.4 μM, respectively.”
Quoted verbatim from Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers.. - Study
- in vitro · not in humans
- Population
- human embryonic kidney 293 cells stably expressing OATP1A2
Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers.2018PMID:29480324