Papers/PMID:29480324
Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers.
European journal of clinical pharmacology2018The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
(-)-epigallocatechin 3-gallate — inhibits SLCO1A2
Evidence strength: insufficient.Finding“EGCG competitively inhibited OATP1A2-mediated uptake of sulphobromophthalein and nadolol with Ki values of 21.6 and 19.4 μM, respectively.”
Quoted verbatim from Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers.. - Study
- in vitro · not in humans
- Population
- human embryonic kidney 293 cells stably expressing OATP1A2
Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers.2018PMID:2948032410.1007/s00228-018-2436-2Permalink