Papers/PMID:28916479
Dietary Nitrate Increases VO2peak and Performance but Does Not Alter Ventilation or Efficiency in Patients With Heart Failure With Reduced Ejection Fraction.
Journal of cardiac failure2018The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
nitrate — increases plasma nitrite concentration
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.Findingreplicated ×8“Concentrations of the downstream metabolites of NO3-, i.e., plasma NO2- and breath NO, were also significantly elevated by NO3- intake, albeit to a much lesser degree (, middle and bottom panels).”
Quoted verbatim from Dietary Nitrate Increases VO2peak and Performance but Does Not Alter Ventilation or Efficiency in Patients With Heart Failure With Reduced Ejection Fraction.. - Study
- crossover
- Dose
- 140 mL concentrated beetroot juice, 11.2 mmol nitrate, single dose, tested 2 h post-ingestion
- Population
- 8 patients with heart failure with reduced ejection fraction (HFrEF), acute single dose
Dietary Nitrate Increases VO2peak and Performance but Does Not Alter Ventilation or Efficiency in Patients With Heart Failure With Reduced Ejection Fraction.2018PMID:28916479Permalink
nitrate — increases maximal oxygen uptake
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“This improvement in exercise performance was accompanied by a moderate, but potentially clinically-significant (see Discussion), increase in VO2peak, expressed in either L/min (P<0.05; Table 3) or in mL.min-1.kg-1 (P < 0.05; Fig. 4, bottom panel).”
Quoted verbatim from Dietary Nitrate Increases VO2peak and Performance but Does Not Alter Ventilation or Efficiency in Patients With Heart Failure With Reduced Ejection Fraction.. - Study
- crossover
- Dose
- 140 mL concentrated beetroot juice, 11.2 mmol nitrate, single dose, tested 2 h post-ingestion
- Population
- 8 patients with heart failure with reduced ejection fraction (HFrEF), acute single dose, maximal incremental cycle ergometer test
Dietary Nitrate Increases VO2peak and Performance but Does Not Alter Ventilation or Efficiency in Patients With Heart Failure With Reduced Ejection Fraction.2018PMID:28916479Permalink