Papers/PMID:28891953
The Effect of Vitamin A on Fracture Risk: A Meta-Analysis of Cohort Studies.
International journal of environmental research and public health2017The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
all-trans-retinol — increases hip fracture incidence
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×2“Pooled results showed that the increased retinol intake might decrease the risk of total fracture (RR with 95% CI: 0.95 (0.91, 1.00)) and increase the risk of hip fracture (RR with 95% CI: 1.40 (1.02, 1.91)).”
Quoted verbatim from The Effect of Vitamin A on Fracture Risk: A Meta-Analysis of Cohort Studies.. - Study
- meta-analysis
- Dose
- highest versus lowest category of retinol intake
- Population
- Adults over 20 years in prospective cohort and nested case-control studies; dietary retinol intake, highest versus lowest category, four studies reporting hip fracture
Effect 1.4 risk ratio, 95% CI 1.02 to 1.91
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