Papers/PMID:28686188
Dietary Choline and Betaine and Risk of CVD: A Systematic Review and Meta-Analysis of Prospective Studies.
Nutrients2017The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
choline — no detected effect on incidence of cardiovascular disease (composite)
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“In random-effects meta-analysis, choline was not associated with any incident CVD (relative risk (RR): 1.00 (95% CI: 0.98, 1.02) for an increase of 100 mg/day choline intake).”
Quoted verbatim from Dietary Choline and Betaine and Risk of CVD: A Systematic Review and Meta-Analysis of Prospective Studies.. - Study
- meta-analysis
- Dose
- dietary intake, per 100 mg/day increment of choline
- Population
- Adults in five prospective cohorts (USA, Netherlands, Japan) with dietary choline from food frequency questionnaires; observational dose-response per 100 mg/day, not an administered dose
Effect 1 risk ratio, 95% CI 0.98 to 1.02
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