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PapersPMID:28471488

Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort.

Depression and anxiety2017The record ↗

  1. Finding, moderate evidenceraisesEdinburgh Postnatal Depression Scale (EPDS) total score

What moved

1 findingHow to read these marks →
  • “Linear regression models showed statistically significant positive associations between antenatal plasma choline concentrations and antenatal depression scores in crude and multivariate adjusted models [model 3: β= 0.24 EPDS score (95% CI 0.05-0.043) per µmol/L: Table 2].”
    Study
    cohort
    Population
    Pregnant women in the GUSTO cohort, Singapore; maternal plasma free choline at 26-28 weeks gestation against EPDS at the same visit (antenatal), adjusted model 3

Study record

Design
cohort study
Species
human
Population
Pregnant women in the GUSTO mother-offspring cohort, Singapore, with plasma choline and betaine at 26-28 weeks gestation
Participants
949
Comparator
observational
Duration
not reported
Endpoints measured
24