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Catalyst

cholineFinding

Choline increases Edinburgh Postnatal Depression Scale (EPDS) total score

raisesModerate evidenceFinding

01 · The sentence it was drawn from

“Linear regression models showed statistically significant positive associations between antenatal plasma choline concentrations and antenatal depression scores in crude and multivariate adjusted models [model 3: β= 0.24 EPDS score (95% CI 0.05-0.043) per µmol/L: Table 2].”
Quoted verbatim from Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort.
This finding among the 1 finding on its endpoint

choline

Edinburgh Postnatal Depression Scale (EPDS) total score

raises

Who
Pregnant women in the GUSTO cohort, Singapore; maternal plasma free choline at 26-28 weeks gestation against EPDS at the same visit (antenatal), adjusted model 3
Dose studied
not reported

Moderate evidencePMID 28471488 · 2017

02 · The study

Study
cohort
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Depression and anxiety
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M7017JK5NKNZ4DVKSRVFY9SQ