Papers/PMID:28265298
Safety and effectiveness of propranolol in severely burned patients: systematic review and meta-analysis.
World journal of emergency surgery : WJES2017The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
propranolol — no detected effect on all-cause mortality
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“There were no significant differences between propranolol and placebo/usual care with respect to mortality (RD −0.02 [95% CI −0.06 to 0.02]), and also, no differences were found in the sub-group analysis when assessing this outcome in children (RD −0.02 [95% CI −0.06 to 0.02]) and adults (RD −0.05 [95% CI −0.17 to 0.07]).”
Quoted verbatim from Safety and effectiveness of propranolol in severely burned patients: systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Severely burned adults and children (TBSA >20%) in randomised trials of propranolol versus placebo or usual care; four trials reported mortality
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