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PapersPMID:28070018

Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress.

Aging2017The record ↗

01 · finding
1
02 · compound
1
03 · endpoint
1
04 · null
1
  1. Finding, moderate evidenceno effectCarotid-femoral pulse wave velocity

Every finding here is a null result.

What did not

1 findingHow to read these marks →
  • curcumin — no detected effect on carotid-femoral pulse wave velocity

    moderateFindingNull result

    “There was no group by time interaction for aortic PWV (P=0.8), carotid artery compliance (P=0.2), or other arterial stiffness parameters (all P>0.2).”
    Quoted verbatim from Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress.
    Study
    RCT
    Duration
    3 months
    Dose studied
    2000 mg/day Longvida® curcumin (~400 mg curcumin), once daily for 12 weeks
    Population
    healthy middle-aged and older adults, 45-74 years

    Permalink

Study record

Read under
curcumin
Design
randomised controlled trial
Species
human
Population
healthy men and postmenopausal women aged 45-74 with age-related conduit artery endothelial dysfunction (screening brachial artery FMD <7%), Boulder County, Colorado
Participants
39
Comparator
placebo
Duration
84 days
Endpoints measured
9
Record
extracted
Readings recorded
2