Skip to content
Catalyst

PapersPMID:27177615

A dietary cholesterol challenge study to assess Chlorella supplementation in maintaining healthy lipid levels in adults: a double-blinded, randomized, placebo-controlled study.

Nutrition journal2016The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, moderate evidencelowersTotal cholesterol (TC)
  2. Finding, limited evidencelowersLDL cholesterol
Study, every finding
RCT · 4 weeks
Dose studied, every finding
5 g/day, 12 tablets with meals
Population, every finding
Healthy young adults (mean age about 23, 30 of 34 women) on a 3-egg-a-day (510 mg cholesterol) dietary cholesterol challenge in both arms, 4 weeks
  • “In contrast, concomitant ingestion of 5 g Chlorella significantly suppressed the increases of TC (9.8 % versus 3.5 %; P = 0.037 for interaction) and LDL-C (14.3 % versus 1.7 %; P = 0.012 for interaction), but accelerated the increase of HDL-C (3.8 % versus 8.3 %), a finding that lacked statistical significance (Table 3, upper part).”

Study record

Design
randomised controlled trial
Species
human
Population
Healthy young adults (mostly women) with serum total cholesterol < 5.18 mmol/L at screening, given a 3-egg/day dietary cholesterol challenge
Participants
34
Comparator
placebo
Duration
28 days
Endpoints measured
20