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Catalyst

PapersPMID:26537218

Supplementation of krill oil with high phospholipid content increases sum of EPA and DHA in erythrocytes compared with low phospholipid krill oil.

Lipids in health and disease2015The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, limited evidenceraisesOmega-3 index (erythrocyte membrane)
  2. Finding, limited evidenceraisesLDL cholesterol
Study, every finding
crossover · 4 weeks
Dose studied, every finding
3 g/day high-phospholipid krill oil for 4 weeks, 8-week washout between phases
Population, every finding
Healthy adult volunteers in a semi-randomised, single-blind crossover trial; high-phospholipid krill oil arm against corn oil control, 4 weeks per phase
  • “Intake of HPL krill oil significantly increased RBC concentrations of EPA (p < 0.001), DHA (p = 0.017), EPA + DHA (the omega-3 index, p < 0.001) and n-3 PUFA (p < 0.001) compared to control.”
  • “However, HPL krill oil supplementation elevated serum total (p = 0.024) and LDL cholesterol concentrations (p < 0.001) compared to control.”

Study record

Design
crossover trial
Species
human
Population
Healthy volunteers; low phospholipid krill oil (LPL), high phospholipid krill oil (HPL) and corn oil control, semi-randomized crossover
Participants
20
Comparator
placebo
Duration
not reported
Endpoints measured
56