PapersPMID:25019209
An examination of resveratrol's mechanisms of action in human tissue: impact of a single dose in vivo and dose responses in skeletal muscle ex vivo.
resveratrolNo finding here moved its endpoint.
What did not
1 findingHow to read these marks →- Activates SIRT1
moderate
“No effect of time (fasted vs. post-prandial) or RSV was observed for nuclear SIRT1 activity.”
- Study
- crossover
- Dose studied
- single dose 300 mg resveratrol (resVida) with breakfast vs microcrystalline cellulose placebo, 7-day washout
- Population
- Eight sedentary overweight or obese men, vastus lateralis biopsy fasted and 2 h after a meal with a single capsule
Study record
- Design
- crossover trial
- Species
- human
- Population
- Experiment 1: eight sedentary overweight/obese men given a single 300 mg resveratrol dose or placebo with a meal (randomized crossover); Experiment 2: eight lean recreationally active men, permeabilized muscle fibre bundles titrated ex vivo with resveratrol
- Participants
- 16
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 21