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Catalyst

resveratrolFinding

Resveratrol activates SIRT1

no difference foundModerate evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“No effect of time (fasted vs. post-prandial) or RSV was observed for nuclear SIRT1 activity.”
Quoted verbatim from An examination of resveratrol's mechanisms of action in human tissue: impact of a single dose in vivo and dose responses in skeletal muscle ex vivo.
This finding among the 3 findings on its endpoint

resveratrol

SIRT1

no difference found

Who
Eight sedentary overweight or obese men, vastus lateralis biopsy fasted and 2 h after a meal with a single capsule
Dose studied
single dose 300 mg resveratrol (resVida) with breakfast vs microcrystalline cellulose placebo, 7-day washout

Moderate evidencePMID 25019209 · 2014

02 · The study

Study
crossover
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

PloS one
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6XKAG3K8CRD00HAXZTY9CGZ