Papers/PMID:25009784
Biochemical responses and mitochondrial mediated activation of apoptosis on long-term effect of aspartame in rat brain.
Redox biology2014The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
aspartame — activates CAT
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“The activity of catalase was increased markedly in all the regions of brain (cerebral cortex (F = 27, df = 2), cerebellum(F = 34, df = 2), midbrain (F = 53, df = 2), pons-medulla (F = 14, df = 2), hippocampus (F = 25, df = 2) and hypothalamus (F = 50, df = 2)) in aspartame treated MTX animals with respect to control and MTX treated control.”
Quoted verbatim from Biochemical responses and mitochondrial mediated activation of apoptosis on long-term effect of aspartame in rat brain.. - Study
- animal · not in humans
- Population
- Male Wistar rats given methotrexate; aspartame-plus-methotrexate group versus saline control and methotrexate-only control; six brain regions, tissue assay
Biochemical responses and mitochondrial mediated activation of apoptosis on long-term effect of aspartame in rat brain.2014PMID:25009784Permalink