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Catalyst

PapersPMID:24696187

Magnesium supplementation in pregnancy.

The Cochrane database of systematic reviews2014The record ↗

  1. Finding, very limited evidenceno difference foundPre-eclampsia incidence

No finding here moved its endpoint.

What did not

1 findingHow to read these marks →
  • “In the analysis of all trials, oral magnesium supplementation compared to no magnesium was associated with no significant difference in perinatal mortality (stillbirth and neonatal death prior to discharge) (risk ratio (RR) 1.10; 95% confidence interval (CI) 0.72 to 1.67; five trials, 5903 infants), small-for-gestational age (RR 0.76; 95% CI 0.54 to 1.07; three trials, 1291 infants), or pre-eclampsia (RR 0.87; 95% CI 0.58 to 1.32; three trials, 1042 women).”
    Study
    meta-analysis
    Participants
    1,042
    Effect
    0.87 risk ratio, 95% CI 0.58 to 1.32
    Dose studied
    oral magnesium supplement, pooled forms (oxide, citrate, gluconate, aspartate, stearate) and doses
    Population
    Pregnant women in three randomised and quasi-randomised trials of oral magnesium supplementation versus placebo or no treatment

Study record

Design
meta-analysis
Species
human
Population
Pregnant women and their babies in 10 randomised or quasi-randomised trials of oral magnesium supplementation
Participants
9,090
Comparator
not stated in the paper / placebo
Duration
not reported
Endpoints measured
9
Declined
this platform holds no node for the endpoint