PapersPMID:22099425
Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial.
- 01 · finding
- 1
- 02 · compound
- 1
- 03 · endpoint
- 1
- 04 · null
- 0
curcuminWhat moved
1 findingHow to read these marks →curcumin — decreases catalase activity
very limitedFinding
“Serum concentrations of substance P (P<0·001) as well as activities of superoxide dismutase (P=0·02), glutathione peroxidase (P=0·006) and catalase (P<0·001) were significantly reduced in the curcumin group, while no significant change was observed in the placebo group.”
Quoted verbatim from Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial. - Study
- RCT
- Duration
- 4 weeks
- Dose studied
- 1 g/d
- Population
- male Iranian veterans with sulphur mustard-induced chronic pruritus
Study record
- Read under
- curcumin
- Design
- randomised controlled trial
- Species
- human
- Population
- male Iranian veterans (age 37-59 years) with sulphur mustard-induced chronic pruritic skin lesions
- Participants
- 96
- Comparator
- placebo
- Duration
- 28 days
- Endpoints measured
- 8
- Record
- extracted
- Readings recorded
- 2