Papers/PMID:21868478
Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis.
BMJ (Clinical research ed.)2011The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
all-trans-retinol — decreases all-cause mortality
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×10“Vitamin A was associated with a 24% reduction in all cause mortality (0.76, 95% confidence interval 0.69 to 0.83; fig 3), though there was moderate heterogeneity (χ2=29.10, df=15, P=0.02; I2=48%).”
Quoted verbatim from Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis.. - Study
- meta-analysis
- Dose
- synthetic oral vitamin A, mostly 100,000 IU (<12 months) or 200,000 IU (older) every 4 to 6 months, some single dose or weekly
- Population
- Apparently healthy children aged 6 months to 5 years in 16 randomised trials of prophylactic synthetic oral vitamin A versus placebo or no treatment; all-cause mortality at longest follow-up (mostly about one year)
Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis.2011PMID:21868478An author is affiliated with a producerPermalink