Papers/PMID:21731668
Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.
PloS one2011The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
L-leucine — no detected effect on body weight gain over a feeding or growth period
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.FindingNull result“Doubling dietary leucine reversed many of the metabolite abnormalities and caused a marked improvement in glucose tolerance and insulin signaling without altering food intake or weight gain.”
Quoted verbatim from Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.. - Study
- animal · not in humans
- Dose
- dietary leucine doubled by addition to drinking water
- Population
- Mice on a high-fat diet for 8 weeks, with dietary leucine doubled by addition to the drinking water, compared with high-fat diet mice on unsupplemented drinking water
Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.2011PMID:21731668Permalink