PapersPMID:1987006
Sodium chloride raises blood pressure in normotensive subjects. The study of sodium and blood pressure.
- findings
- 2
- compound
- 1
- endpoints
- 2
- Study, every finding
- crossover · 4 weeks
- Dose studied, every finding
- sodium capsules, 96 meq sodium per day, against placebo capsules
- Population, every finding
- Normotensive adults on a low sodium diet continued through both capsule periods in both arms; 4-week periods separated by a 2-week washout
What moved
How to read these marks →“Both systolic and diastolic blood pressures increased significant amounts in normotensive adults on a low sodium diet supplemented with 96 meq/day sodium.”
- Increases systolic blood pressure
very limited
- Increases diastolic blood pressure
very limited
Study record
- Design
- crossover trial
- Species
- human
- Population
- Normotensive adults on a low sodium diet (urinary sodium under 35 meq/8 hr target), 79% male
- Participants
- 48
- Comparator
- placebo
- Duration
- 28 days
- Endpoints measured
- 3