Papers/PMID:19221011
Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.
American journal of physiology. Gastrointestinal and liver physiology2009The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
sucralose — no detected effect on gastric emptying rate
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Gastric emptying of sucrose was slower than that of saline (t50: 87.4+/-4.1 min vs. 74.7+/-3.2 min, P<0.005), whereas there were no differences in t50 between sucralose 0.4 mM (73.7+/-3.1 min) or 4 mM (76.7+/-3.1 min) and saline.”
Quoted verbatim from Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.. - Study
- crossover
- Dose
- single intragastric infusion of 80 mg (0.4 mM) or 800 mg (4 mM) sucralose in 500 ml normal saline
- Population
- Healthy adults; intragastric infusions of 500 ml, gastric emptying by 13C-acetate breath test
Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.2009PMID:19221011Permalink