Papers/PMID:17662090
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
British journal of clinical pharmacology2008The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
L-citrulline — increases plasma arginine concentration
Evidence strength: very limited.Findingreplicated ×1“Our data show for the first time that oral L-citrulline supplementation raises plasma L-arginine concentration and augments NO-dependent signalling in a dose-dependent manner.”
Quoted verbatim from Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.. - Study
- crossover
- Duration
- 7 days
- Population
- 20 healthy volunteers in a double-blind, randomized, placebo-controlled cross-over study of six dosing regimes of placebo, citrulline and arginine
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.2008PMID:1766209010.1111/j.1365-2125.2007.02990.xPermalink