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PapersPMID:17298708

Effect of phylloquinone supplementation on biochemical markers of vitamin K status and bone turnover in postmenopausal women.

The British journal of nutrition2007The record ↗

  1. Finding, very limited evidencelowersSerum undercarboxylated osteocalcin concentration

What moved

1 findingHow to read these marks →
  • “With increasing phylloquinone intake, the concentration of serum gamma-carboxylated and under-gamma-carboxylated osteocalcin was significantly increased and decreased, respectively, in a dose-dependent manner (P < 0.001).”
    Study
    crossover
    Duration
    6 weeks
    Dose studied
    0 (placebo), 200 and 500 microg phylloquinone/d, 6 weeks each
    Population
    Postmenopausal women in a 3 x 6-week randomised cross-over study; all periods included 10 microg vitamin D3/d; dose-dependent across placebo, 200 and 500 microg/d

Study record

Design
crossover trial
Species
human
Population
postmenopausal women
Participants
31
Comparator
placebo
Duration
42 days
Endpoints measured
11