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phylloquinoneFinding

Phylloquinone decreases serum undercarboxylated osteocalcin concentration

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“With increasing phylloquinone intake, the concentration of serum gamma-carboxylated and under-gamma-carboxylated osteocalcin was significantly increased and decreased, respectively, in a dose-dependent manner (P < 0.001).”
Quoted verbatim from Effect of phylloquinone supplementation on biochemical markers of vitamin K status and bone turnover in postmenopausal women.
This finding among the 2 findings on its endpoint

phylloquinone

Serum undercarboxylated osteocalcin concentration

lowers

Who
Postmenopausal women in a 3 x 6-week randomised cross-over study; all periods included 10 microg vitamin D3/d; dose-dependent across placebo, 200 and 500 microg/d
Dose studied
0 (placebo), 200 and 500 microg phylloquinone/d, 6 weeks each

Very limited evidencePMID 17298708 · 2007

02 · The study

Study
crossover
Duration
6 weeks

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

The British journal of nutrition
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M71FQYATKY2KVCF0WPQ3JA8P