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Catalyst

PapersPMID:16856052

Magnesium supplementation for the management of essential hypertension in adults.

The Cochrane database of systematic reviews2006The record ↗

  1. Finding, very limited evidencelowersDiastolic blood pressure

What moved

1 findingHow to read these marks →
  • Decreases diastolic blood pressure

    very limitedreplicated ×6

    “Combining all trials, participants receiving magnesium supplements as compared to control did not significantly reduce SBP (mean difference: -1.3 mmHg, 95% CI: -4.0 to 1.5, I(2)=67%), but did statistically significantly reduce DBP (mean difference: -2.2 mmHg, 95% CI: -3.4 to -0.9, I(2)=47%).”
    Study
    meta-analysis
    Effect
    −2.2 mean difference, 95% CI −3.4 to −0.9
    Dose studied
    oral magnesium supplementation, doses varied across trials
    Population
    Adults with primary hypertension; pooled randomized trials of oral magnesium supplementation versus placebo, no treatment or usual care

Study record

Design
meta-analysis
Species
human
Population
12 RCTs (n=545), adults with primary hypertension, 8-26 weeks follow-up
Participants
545
Comparator
placebo
Duration
not reported
Endpoints measured
2