Papers/PMID:11158948
Effect of ascorbic acid treatment on conduit vessel endothelial dysfunction in patients with hypertension.
American journal of physiology. Heart and circulatory physiology2001The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
L-ascorbic acid — no detected effect on flow-mediated dilation
Evidence strength: very limited.FindingNull result“However, acute or chronic ascorbic acid treatment had no effect on brachial artery endothelium-dependent, flow-mediated dilation or on endothelium-independent, nitroglycerin-mediated dilation.”
Quoted verbatim from Effect of ascorbic acid treatment on conduit vessel endothelial dysfunction in patients with hypertension.. - Study
- RCT
- Dose
- acute 2 g orally; chronic 500 mg/day for 1 month
- Population
- Patients with hypertension and impaired brachial artery flow-mediated dilation; acute and chronic treatment reported together
Effect of ascorbic acid treatment on conduit vessel endothelial dysfunction in patients with hypertension.2001PMID:1115894810.1152/ajpheart.2001.280.2.H528Permalink