Reactions

Reactions

6 reactions in Phenylalanine metabolism

• Phenylalanine Transaminase, Mitochondrial

  AKG[m] + phenylalanine[m] = glutamate[m] + phenylpyruvate[m]

  ⇌ ReversibleBalancedEC 2.6.1.58Human-GEM MAR01616

• Formation of Phenyl-Lactate

  NAD+[c] + Phenyllactate[c] = H+[c] + NADH[c] + phenylpyruvate[c]

  ⇌ ReversibleBalancedEC 1.1.1.28Human-GEM MAR09936

• Hydroxylation of 3- (3-Hydroxyphenyl)Propionate

  H+[c] + NADPH[c] + O2[c] + 3-(3-Hydroxy-Phenyl)Propionate[c] = H2O[c] + NADP+[c] + 3-(3-Hydroxy-Phenyl)Propionate Hydroxy Derivative[c]

  → Left to rightBalancedEC 3.1.1.4Human-GEM MAR09971

• Glucuronidation of 3- (3-Hydroxyphenyl)Propionate Hydroxy Derivative

  UDP-glucuronate[c] + 3-(3-Hydroxy-Phenyl)Propionate Hydroxy Derivative[c] = H+[c] + UDP[c] + 3-(3-Hydroxy-Phenyl)Propionate Hydroxy Derivative Glucuronide[c]

  → Left to rightBalancedHuman-GEM MAR10443

• Glycine-N-Acetyltransferase

  glycine[m] + phenylacetyl-CoA[m] = CoA[m] + H+[m] + phenylacetylglycine[m]

  Reversible