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Subsystem: Cysteine and methionine metabolism Remove
46 reactions in Cysteine and methionine metabolism
ATP[c] + H2O[c] + methionine[c] = Pi[c] + PPi[c] + SAM[c]
Left to rightBalancedEC 2.5.1.6Human-GEM MAR03875
H2O[c] + SAH[c] = adenosine[c] + homocysteine[c]
Left to rightBalancedEC 3.13.2.1Human-GEM MAR03877
homocysteine[c] + serine[c] = H2O[c] + L-cystathionine[c]
Left to rightBalancedEC 4.2.1.22Human-GEM MAR03879
H2O[c] + L-cystathionine[c] = 2-oxobutyrate[c] + cysteine[c] + H+[c] + NH3[c]
Left to rightBalancedEC 4.4.1.1Human-GEM MAR03881
AKG[c] + cysteine[c] = glutamate[c] + mercaptopyruvate[c]
ReversibleBalancedEC 2.6.1.1, 2.6.1.3Human-GEM MAR03912
5-methyl-THF[c] + homocysteine[c] = H+[c] + methionine[c] + THF[c]
Left to rightBalancedEC 2.1.1.13Human-GEM MAR03917
H2O[c] + N-acetylmethionine[c] = acetate[c] + methionine[c]
ReversibleBalancedEC 3.5.1.14Human-GEM MAR03919
H2O[c] + homocysteine-thiolactone[c] = H+[c] + homocysteine[c]
ReversibleBalancedEC 3.1.1.2Human-GEM MAR03920
CoA[m] + H+[m] + N-acetyl-L-cystathionine[m] = acetyl-CoA[m] + L-cystathionine[m]
ReversibleBalancedEC 2.3.1.1Human-GEM MAR03922
H+[c] + mercaptopyruvate[c] + sulfite[c] = H2S2O3[c] + pyruvate[c]
Left to rightBalancedEC 2.8.1.2Human-GEM MAR03928
cystine[c] + H+[c] + NADPH[c] = 2 cysteine[c] + NADP+[c]
ReversibleBalancedEC 1.8.1.9Human-GEM MAR03995
cystine[c] + H+[c] + NADH[c] = 2 cysteine[c] + NAD+[c]
ReversibleBalancedEC 1.8.1.6Human-GEM MAR03996
DNA[c] + SAM[c] = DNA-5-methylcytosine[c] + H+[c] + SAH[c]
Left to rightBalance undeterminableEC 2.1.1.37Human-GEM MAR04072
H2O[m] + O2[m] + sulfite[m] = H2O2[m] + sulfate[m]
Left to rightBalancedEC 1.8.3.1Human-GEM MAR04189
cysteine[c] + H2O[c] = 2 H+[c] + H2S[c] + NH3[c] + pyruvate[c]
Left to rightBalancedEC 4.4.1.1, 4.4.1.13Human-GEM MAR04302
H+[c] + H2S[c] + serine[c] = cysteine[c] + H2O[c]
Left to rightBalancedEC 4.2.1.22Human-GEM MAR04323
PAPS[c] + thioredoxin[c] = 2 H+[c] + oxidized thioredoxin[c] + PAP[c] + sulfite[c]
Left to rightBalancedEC 2.8.2.-Human-GEM MAR05381
methylthioribose-1p[c] = S-methyl-5-thio-D-ribulose-1-phosphate[c]
Left to rightBalancedEC 5.3.1.23Human-GEM MAR05385
S-methyl-5-thio-D-ribulose-1-phosphate[c] = 2,3-diketo-5-methylthiopentyl-1-phosphate[c] + H2O[c]
Left to rightBalancedEC 4.2.1.109Human-GEM MAR05386
2,3-diketo-5-methylthiopentyl-1-phosphate[c] + H2O[c] = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one[c] + Pi[c]
Left to rightBalancedEC 3.1.3.77Human-GEM MAR05387
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one[c] + O2[c] = 3-(methylthio)propionic acid[c] + CO[c] + formate[c] + 2 H+[c]
Left to rightBalancedEC 1.13.11.53Human-GEM MAR05388
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one[c] + O2[c] = 4-methylthio-2-oxobutanoic acid[c] + formate[c] + 2 H+[c]
Left to rightBalancedEC 1.13.11.54Human-GEM MAR05389
H2O[c] + methionine[c] + O2[c] = 4-methylthio-2-oxobutanoic acid[c] + H+[c] + H2O2[c] + NH3[c]
Left to rightBalancedEC 1.4.3.2Human-GEM MAR05390
4-methylthio-2-oxobutanoic acid[c] + glutamate[c] = AKG[c] + methionine[c]
Left to rightBalancedEC 2.6.1.5Human-GEM MAR05391
CoA[m] + H+[m] + N-acetylmethionine[m] = acetyl-CoA[m] + methionine[m]
ReversibleBalancedEC 2.3.1.1Human-GEM MAR05418
CoA[m] + H+[m] + N-acetyl-L-cysteine[m] = acetyl-CoA[m] + cysteine[m]
ReversibleBalancedEC 2.3.1.1Human-GEM MAR05419
mercaptopyruvate[c] + sulfite[c] = pyruvate[c] + thiosulfate[c]
Left to rightBalancedEC 2.8.1.2Human-GEM MAR06515
hydrogen-cyanide[c] + mercaptopyruvate[c] = H+[c] + pyruvate[c] + thiocyanate[c]
Left to rightBalancedEC 2.8.1.2Human-GEM MAR06518
3-mercaptolactate[c] + NAD+[c] = H+[c] + mercaptopyruvate[c] + NADH[c]
ReversibleBalancedEC 1.1.1.27Human-GEM MAR06519
hydrogen-cyanide[m] + thiosulfate[m] = H+[m] + sulfite[m] + thiocyanate[m]
ReversibleBalancedEC 2.8.1.1Human-GEM MAR06520
H+[c] + H2O2[c] + thiocyanate[c] = H2O[c] + hypothiocyanite[c]
ReversibleBalancedEC 1.11.1.7, 1.2.4.4, 1.8.1.4Human-GEM MAR06523
dehydroalanine[c] + NADPH[c] + PAPS[c] = L-cysteate[c] + NADP+[c] + PAP[c]
Left to rightBalancedEC 2.8.2.1Human-GEM MAR08062
3-sulfopyruvate[c] + glutamate[c] = AKG[c] + L-cysteate[c]
ReversibleBalancedEC 2.6.1.1, 2.6.1.3Human-GEM MAR08066
3-sulfopyruvate[m] + glutamate[m] = AKG[m] + L-cysteate[m]
ReversibleBalancedEC 2.6.1.1, 2.6.1.3Human-GEM MAR08067
(S)-3-sulfolactate[c] + NAD+[c] = 3-sulfopyruvate[c] + H+[c] + NADH[c]
ReversibleBalancedEC 1.1.1.37Human-GEM MAR08068
(S)-3-sulfolactate[m] + NAD+[m] = 3-sulfopyruvate[m] + H+[m] + NADH[m]
ReversibleBalancedEC 1.1.1.37Human-GEM MAR08069
DNA[n] + SAM[n] = DNA-5-methylcytosine[n] + H+[n] + SAH[n]
Left to rightBalance undeterminableEC 2.1.1.37Human-GEM MAR08641
cystine[c] + 2 GSH[c] = 2 cysteine[c] + GSSG[c]
ReversibleBalancedHuman-GEM MAR08682
cystine[c] + H2O[c] = H+[c] + NH3[c] + pyruvate[c] + thiocysteine[c]
Left to rightBalancedEC 4.4.1.1, 4.4.1.13, 4.4.1.35Human-GEM MAR08683
AKG[m] + cysteine[m] = glutamate[m] + mercaptopyruvate[m]
ReversibleBalancedEC 2.6.1.1Human-GEM MAR08684
3-mercaptolactate[c] + cysteine[c] + NAD+[c] = 3-mercaptolactate-cysteine-disulfide[c] + H+[c] + NADH[c]
Left to rightBalancedHuman-GEM MAR08685
2 hypotaurine[e] + O2[e] = 2 taurine[e]
Left to rightBalancedHuman-GEM MAR08974
cysteine[c] + H+[c] + sulfite[c] = S-Sulfo-L-Cysteine[c]
ReversibleBalancedHuman-GEM MAR08993
methionine[c] + pyruvate[c] = alanine[c] + 4-Methyl-Thio-Oxo-Butyrate[c]
ReversibleBalancedEC 3.1.1.3Human-GEM MAR09953
H+[c] + 4-Methyl-Thio-Oxo-Butyrate[c] = CO2[c] + 3-Methyl-Thio-Propionate[c]
Left to rightBalancedEC 3.1.1.3Human-GEM MAR09954
2 GSH[c] + L-Homocystine[c] = GSSG[c] + 2 homocysteine[c]
ReversibleBalancedHuman-GEM MAR11299