Reactions

Reactions

4 reactions in Cholesterol biosynthesis 2

• lanosterol D24-reductase

  5alpha-cholesta-7,24-dien-3beta-ol[c] + H+[c] + NADPH[c] = lathosterol[c] + NADP+[c]

  → Left to rightBalancedEC 1.3.1.72Human-GEM MAR01533

• lathosterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating

  H+[c] + lathosterol[c] + NADH[c] + O2[c] = 2 H2O[c] + NAD+[c] + provitamin D3[c]

  → Left to rightBalancedEC 1.14.19.20Human-GEM MAR01557

• lathosterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating

  H+[c] + lathosterol[c] + NADPH[c] + O2[c] = 2 H2O[c] + NADP+[c] + provitamin D3[c]

  → Left to rightBalancedEC 1.14.19.20Human-GEM MAR01558

• cholesterol:NADP+ delta7-oxidoreductase

  H+[c] + NADPH[c] + provitamin D3[c] = cholesterol[c] + NADP+[c]

  → Left to rightBalancedEC 1.3.1.21Human-GEM MAR01565