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Subsystem: Vitamin D metabolism Remove
34 reactions in Vitamin D metabolism
provitamin D3[c] = vitamin D3[c]
Left to rightBalancedHuman-GEM MAR02114
H+[c] + NADPH[c] + O2[c] + vitamin D3[c] = calcidiol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.24Human-GEM MAR02115
H+[m] + NADPH[m] + O2[m] + vitamin D3[m] = calcidiol[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02117
calcidiol[c] + H+[c] + NADPH[c] + O2[c] = calcitriol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.15.18Human-GEM MAR02118
calcidiol[c] + H+[c] + NADPH[c] + O2[c] = 23s,25-dihydroxyvitamin D3[c] + H2O[c] + NADP+[c]
Left to rightBalanced
23s,25-dihydroxyvitamin D3[m] + H2O[m] + NADP+[m] = calcidiol[m] + H+[m] + NADPH[m] + O2[m]
ReversibleBalancedEC 1.14.13.-Human-GEM MAR02130
23s,25-dihydroxyvitamin D3[c] + H+[c] + NADH[c] + O2[c] = 23S,25,26-trihydroxyvitamin D3[c] + H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02131
23s,25-dihydroxyvitamin D3[m] + H+[m] + NADH[m] + O2[m] = 23S,25,26-trihydroxyvitamin D3[m] + H2O[m] + NAD+[m]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02132
23S,25,26-trihydroxyvitamin D3[c] + O2[c] = 25-hydroxyvitamin D3-26,23-lactol[c] + H2O2[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02133
23S,25,26-trihydroxyvitamin D3[m] + O2[m] = 25-hydroxyvitamin D3-26,23-lactol[m] + H2O2[m]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02134
25-hydroxyvitamin D3-26,23-lactol[c] + O2[c] = 25-hydroxyvitamin D3-26,23-lactone[c] + H2O2[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02135
25-hydroxyvitamin D3-26,23-lactol[m] + O2[m] = 25-hydroxyvitamin D3-26,23-lactone[m] + H2O2[m]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02136
calcidiol[c] + H+[c] + NADPH[c] + O2[c] = (24R)-24,25-dihydroxycalciol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.15.16Human-GEM MAR02137
calcidiol[m] + H+[m] + NADPH[m] + O2[m] = (24R)-24,25-dihydroxycalciol[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.16Human-GEM MAR02138
(24R)-24,25-dihydroxycalciol[c] + H+[c] + NADH[c] + O2[c] = calcitetrol[c] + H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.15.16Human-GEM MAR02139
(24R)-24,25-dihydroxycalciol[m] + H+[m] + NADH[m] + O2[m] = calcitetrol[m] + H2O[m] + NAD+[m]
Left to rightBalancedEC 1.14.15.16Human-GEM MAR02140
calcitetrol[c] + H+[c] + NADPH[c] + O2[c] = 24-oxo-1alpha,25-dihydroxyvitamin D3[c] + 2 H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02142
calcitetrol[m] + H+[m] + NADPH[m] + O2[m] = 24-oxo-1alpha,25-dihydroxyvitamin D3[m] + 2 H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02143
24-oxo-1alpha,25-dihydroxyvitamin D3[c] + H+[c] + NADPH[c] + O2[c] = 24-oxo-1alpha,23,25-trihydroxyvitamin D3[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02144
24-oxo-1alpha,25-dihydroxyvitamin D3[m] + H+[m] + NADPH[m] + O2[m] = 24-oxo-1alpha,23,25-trihydroxyvitamin D3[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR02145
(24R)-24,25-dihydroxycalciol[m] + H+[m] + NADH[m] + O2[m] = 23S,25,26-trihydroxyvitamin D3[m] + H2O[m] + NAD+[m]
Left to rightBalancedEC 3.4.24.16Human-GEM MAR02767
NADPH[c] + O2[c] + 24,25,26,27-Tetranor-23-Oxo-Hydroxyvitamin D3[c] = calcitroic acid[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 2.3.1.16Human-GEM MAR03435
NADPH[m] + O2[m] + 24,25,26,27-Tetranor-23-Oxo-Hydroxyvitamin D3[m] = calcitroic acid[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.16Human-GEM MAR03436
H+[m] + NADPH[m] + O2[m] + vitamin D2[m] = 25-hydroxyvitamin D2[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.15Human-GEM MAR07996
25-hydroxyvitamin D2[m] + H+[m] + NADPH[m] + O2[m] = 24R,25-dihyoxyvitamin D2[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.16Human-GEM MAR07999
24R,25-dihyoxyvitamin D2[m] + H+[m] + NADPH[m] + O2[m] = 1-alpha,24R,25-trihydroxyvitamin D2[m] + H2O[m] + NADP+[m]
Left to rightBalancedHuman-GEM MAR08003
25-hydroxyvitamin D2[m] + H+[m] + NADPH[m] + O2[m] = 1-alpha,25-dihydroxyvitamin D2[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.18Human-GEM MAR08004
1-alpha,25-dihydroxyvitamin D2[m] + H+[m] + NADPH[m] + O2[m] = 1-alpha,24R,25-trihydroxyvitamin D2[m] + H2O[m] + NADP+[m]
Left to rightBalancedHuman-GEM MAR08005
(24R)-24,25-dihydroxycalciol[m] + H+[m] + NADPH[m] + O2[m] = calcitetrol[m] + H2O[m] + NADP+[m]
Left to rightBalancedHuman-GEM MAR08006
calcidiol[m] + H+[m] + NADPH[m] + O2[m] = calcitriol[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.18Human-GEM MAR08008
previtamin D3[c] = provitamin D3[c]
ReversibleBalancedHuman-GEM MAR08011
lumisterol 3[c] = previtamin D3[c]
ReversibleBalancedHuman-GEM MAR08012
previtamin D3[c] = tachysterol 3[c]
ReversibleBalancedHuman-GEM MAR08013
previtamin D3[c] = vitamin D3[c]
ReversibleBalancedHuman-GEM MAR08014