Reactions

Reactions

4 reactions in Vitamin B12 metabolism

• Methionine Synthase

  cob(II)alamin[c] + SAM[c] = SAH[c] + Methylcobalamin[c]

  → Left to rightUnbalancedEC 2.1.1.13Human-GEM MAR03138

• aquacob(III)alamin reduction

  2 aquacob(III)alamin[c] + NADH[c] = 2 cob(II)alamin[c] + H+[c] + 2 H2O[c] + NAD+[c]

  → Left to rightBalancedHuman-GEM MAR08613

• ATP:cob(I)alamin Co-beta-adenosyltransferase

  cob(II)alamin[m] + NADH[m] = cob(I)alamin[m] + H+[m] + NAD+[m]

  ⇌ ReversibleUnbalancedEC 2.5.1.17Human-GEM MAR08615

• ATP:cob(I)alamin Co-beta-adenosyltransferase

  ATP[m] + cob(I)alamin[m] + H+[m] = cobamide-coenzyme[m] + triphosphate[m]

  ⇌ ReversibleBalancedEC 2.5.1.17Human-GEM MAR08616