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Subsystem: Pyrimidine metabolism Remove
1–50 of 76 reactions in Pyrimidine metabolism
dGTP[e] + H2O[e] = dGMP[e] + H+[e] + PPi[e]
Left to rightBalancedEC 3.6.1.9Human-GEM MAR02120
dTDP[e] + H2O[e] = dTMP[e] + H+[e] + Pi[e]
ReversibleBalancedEC 3.6.1.5Human-GEM MAR02124
dTTP[e] + H2O[e] = dTDP[e] + H+[e] + Pi[e]
ReversibleBalancedEC 3.6.1.39Human-GEM MAR02125
2-methyl-3-oxopropanoate[m] + alanine[m] = D-3-amino-isobutanoate[m] + pyruvate[m]
ReversibleBalancedEC 2.6.1.40Human-GEM MAR03793
H+[c] + NADPH[c] + oxidized thioredoxin[c] = NADP+[c] + thioredoxin[c]
Left to rightBalancedEC 1.8.1.9Human-GEM MAR03931
ITP[c] + uridine[c] = H+[c] + IDP[c] + UMP[c]
Left to rightBalancedEC 2.7.1.48Human-GEM MAR03969
H2O[c] + UMP[c] = Pi[c] + uridine[c]
Left to rightBalancedEC 3.1.3.5Human-GEM MAR03970
ADP[c] + UTP[c] = ATP[c] + UDP[c]
ReversibleBalancedEC 2.7.4.6Human-GEM MAR04006
ADP[c] + UDP[c] = ATP[c] + UMP[c]
ReversibleBalancedEC 2.7.4.14, 2.7.4.4Human-GEM MAR04008
ADP[c] + CTP[c] = ATP[c] + CDP[c]
ReversibleBalancedEC 2.7.4.6Human-GEM MAR04028
ADP[m] + CTP[m] = ATP[m] + CDP[m]
ReversibleBalancedEC 2.7.4.6Human-GEM MAR04030
ATP[c] + NH3[c] + UTP[c] = ADP[c] + CTP[c] + H+[c] + Pi[c]
Left to rightBalancedEC 6.3.4.2Human-GEM MAR04032
2 ATP[c] + glutamine[c] + H2O[c] + HCO3-[c] = 2 ADP[c] + carbamoyl-phosphate[c] + glutamate[c] + 2 H+[c] + Pi[c]
Left to rightBalancedEC 6.3.5.5Human-GEM MAR04034
H+[c] + orotidine-5-phosphate[c] = CO2[c] + UMP[c]
Left to rightBalancedEC 4.1.1.23Human-GEM MAR04036
H+[c] + N-carbamoyl-L-aspartate[c] + Pi[c] = aspartate[c] + carbamoyl-phosphate[c]
ReversibleBalancedEC 2.1.3.2Human-GEM MAR04050
dTMP[c] + H2O[c] = Pi[c] + thymidine[c]
Left to rightBalancedEC 3.1.3.5, 3.1.3.35Human-GEM MAR04056
H2O[r] + UDP[r] = H+[r] + Pi[r] + UMP[r]
Left to rightBalancedEC 3.6.1.5, 3.6.1.6Human-GEM MAR04059
H2O[e] + UDP[e] = H+[e] + Pi[e] + UMP[e]
Left to rightBalancedEC 3.6.1.5, 3.6.1.6Human-GEM MAR04060
H2O[c] + UDP-glucose[c] = glucose-1-phosphate[c] + 2 H+[c] + UMP[c]
Left to rightBalancedEC 3.6.1.8, 3.6.1.9, 3.6.1.45Human-GEM MAR04127
CMP[c] + H2O[c] = cytidine[c] + Pi[c]
Left to rightBalancedEC 3.1.3.5Human-GEM MAR04177
CMP[e] + H2O[e] = cytidine[e] + Pi[e]
Left to rightBalancedEC 3.1.3.5Human-GEM MAR04179
cytidine[c] + GTP[c] = CMP[c] + GDP[c] + H+[c]
Left to rightBalancedEC 2.7.1.-Human-GEM MAR04182
CDP[e] + H2O[e] = CMP[e] + H+[e] + Pi[e]
Left to rightBalancedEC 3.6.1.5Human-GEM MAR04183
CTP[e] + H2O[e] = CDP[e] + H+[e] + Pi[e]
Left to rightBalancedEC 3.6.1.5Human-GEM MAR04192
ATP[c] + glutamine[c] + H2O[c] + UTP[c] = ADP[c] + CTP[c] + glutamate[c] + 2 H+[c] + Pi[c]
Left to rightBalancedEC 6.3.4.2Human-GEM MAR04194
H+[c] + PEP[c] + UDP[c] = pyruvate[c] + UTP[c]
Left to rightBalancedEC 2.7.1.40Human-GEM MAR04210
H2O[e] + UTP[e] = H+[e] + PPi[e] + UMP[e]
Left to rightBalancedEC 3.6.1.9Human-GEM MAR04211
PRPP[c] + uracil[c] = PPi[c] + UMP[c]
Left to rightBalancedEC 2.4.2.9Human-GEM MAR04343
5,6-Dihydrouracil[c] + NADP+[c] = H+[c] + NADPH[c] + uracil[c]
ReversibleBalancedEC 1.3.1.2Human-GEM MAR04345
5,6-Dihydrouracil[c] + H2O[c] = 3-ureidopropionate[c] + H+[c]
Left to rightBalancedEC 3.5.2.2Human-GEM MAR04346
H+[c] + NADH[c] + thymine[c] = dihydrothymine[c] + NAD+[c]
Left to rightBalancedEC 1.3.1.2Human-GEM MAR04470
H+[m] + NADH[m] + thymine[m] = dihydrothymine[m] + NAD+[m]
Left to rightBalancedEC 1.3.1.2Human-GEM MAR04471
H+[c] + NADPH[c] + thymine[c] = dihydrothymine[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.2Human-GEM MAR04472
dTMP[m] + H2O[m] = Pi[m] + thymidine[m]
Left to rightBalancedEC 3.1.3.5, 3.1.3.35Human-GEM MAR04484
2-deoxy-D-ribose-1-phosphate[c] + thymine[c] = Pi[c] + thymidine[c]
ReversibleBalancedEC 2.4.2.1, 2.4.2.4Human-GEM MAR04485
dCMP[c] + H2O[c] = deoxycytidine[c] + Pi[c]
Left to rightBalancedEC 3.1.3.5Human-GEM MAR04510
ADP[c] + dCDP[c] = ATP[c] + dCMP[c]
ReversibleBalancedEC 2.7.4.14Human-GEM MAR04512
ATP[c] + deoxycytidine[c] = ADP[c] + dCMP[c] + H+[c]
Left to rightBalancedEC 2.7.1.74Human-GEM MAR04513
deoxycytidine[c] + H2O[c] = deoxyuridine[c] + NH3[c]
Left to rightBalancedEC 3.5.4.5Human-GEM MAR04514
(S)-dihydroorotate[c] + FMN[c] = orotate[c] + FMNH2[c]
ReversibleBalancedEC 1.3.5.2, 1.3.1.14Human-GEM MAR04575
orotate[c] + PRPP[c] = orotidine-5-phosphate[c] + PPi[c]
Left to rightBalancedEC 2.4.2.10Human-GEM MAR04577
Pi[c] + uridine[c] = ribose-1-phosphate[c] + uracil[c]
ReversibleBalancedEC 2.4.2.3Human-GEM MAR04579
cytidine[c] + H2O[c] = NH3[c] + uridine[c]
Left to rightBalancedEC 3.5.4.5Human-GEM MAR04580
(S)-dihydroorotate[c] + H2O[c] = H+[c] + N-carbamoyl-L-aspartate[c]
ReversibleBalancedEC 3.5.2.3Human-GEM MAR04608
ADP[c] + dTTP[c] = ATP[c] + dTDP[c]
ReversibleBalancedEC 2.7.4.6Human-GEM MAR04635
ADP[c] + dTDP[c] = ATP[c] + dTMP[c]
ReversibleBalancedEC 2.7.4.12, 2.7.4.9Human-GEM MAR04637
dUMP[c] + H2O[c] = deoxyuridine[c] + Pi[c]
Left to rightBalancedEC 3.1.3.-Human-GEM MAR04642
dUTP[m] + H2O[m] = dUMP[m] + H+[m] + PPi[m]
Left to rightBalancedEC 3.6.1.23, 3.6.1.9Human-GEM MAR04643
5,10-methylene-THF[c] + dUMP[c] = dihydrofolate[c] + dTMP[c]
Left to rightBalancedEC 2.1.1.45Human-GEM MAR04644
ADP[c] + dCTP[c] = ATP[c] + dCDP[c]
ReversibleBalancedEC 2.7.4.6Human-GEM MAR04670