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Subsystem: Linoleate metabolism Remove
35 reactions in Linoleate metabolism
linoleate[c] + O2[c] = 9(S)-HPODE[c]
Left to rightBalancedHuman-GEM MAR02437
9(S)-HPODE[c] + H+[c] + NADPH[c] = 9-hydroxyoctadecadienoate[c] + H2O[c] + NADP+[c]
ReversibleBalancedEC 1.14.99.1Human-GEM MAR02438
linoleate[c] + O2[c] = 11-HpODE[c]
Left to rightBalancedEC 1.13.11.45Human-GEM MAR02439
linoleate[c] + O2[c] = 13(S)-HPODE[c]
Left to rightBalancedEC 1.13.11.12, 1.13.11.33Human-GEM MAR02440
13(S)-HPODE[c] + H+[c] + NADPH[c] = 13(S)-HODE[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.11.1.9Human-GEM MAR02441
13(S)-HPODE[c] + H2O[c] = 4-hydroperoxy-2-nonenal[c] + nonanoic acid[c]
ReversibleBalancedHuman-GEM MAR02442
13(S)-HPODE[c] + ferricytochrome C[c] + H+[c] = 13-oxy-radical-octadecadienoate[c] + ferrocytochrome C[c] + H2O[c]
ReversibleUnbalancedHuman-GEM MAR02443
13-oxo-(9Z,11E)-tridecadienoate[c] + pentyl radical[c] = 13-oxy-radical-octadecadienoate[c]
ReversibleBalancedHuman-GEM MAR02444
12,13-epoxylinoleic acid-radical[c] = 13-oxy-radical-octadecadienoate[c]
ReversibleBalancedHuman-GEM MAR02445
12,13-epoxy-9-hydroperoxy-(10E)-octadecenoate[c] + monodehydroascorbate[c] = 12,13-epoxylinoleic acid-radical[c] + ascorbate[c] + O2[c]
ReversibleBalancedHuman-GEM MAR02446
12,13-epoxy-9-alkoxy-(10E)-octadecenoate[c] + ferricytochrome C[c] + H2O[c] = 12,13-epoxy-9-hydroperoxy-(10E)-octadecenoate[c] + ferrocytochrome C[c] + H+[c]
ReversibleBalancedHuman-GEM MAR02447
12,13-epoxy-9-alkoxy-(10E)-octadecenoate[c] + H+[c] = octanoate radical[c] + trans-4,5-epoxy-(2E)-decenal[c]
ReversibleBalancedHuman-GEM MAR02448
12,13-epoxy-9-alkoxy-(10E)-octadecenoate[c] + H2O[c] = 9,10-12,13-diepoxy-octadecanoate[c] + hydroxide[c]
Left to rightUnbalancedHuman-GEM MAR02449
9,10-12,13-diepoxy-octadecanoate[c] + O2[c] = 1-hydroperoxy-8-carboxyoctyl-3,4-epoxynon-(2E)-enyl-ether[c]
Left to rightBalancedHuman-GEM MAR02450
1-hydroperoxy-8-carboxyoctyl-3,4-epoxynon-(2E)-enyl-ether[c] = 4-oxo-2-nonenal[c] + azelaic acid[c] + 3 H+[c]
ReversibleUnbalancedHuman-GEM MAR02451
1-hydroperoxy-8-carboxyoctyl-3,4-epoxynon-(2E)-enyl-ether[c] = 3,4-epoxynonanal[c] + azelaic acid[c] + H+[c]
ReversibleBalancedHuman-GEM MAR02452
4-hydroperoxy-2-nonenal[c] = 4-oxo-2-nonenal[c] + H2O[c]
ReversibleBalancedHuman-GEM MAR02453
3,4-epoxynonanal[c] = 4-hydroxy-2-nonenal[c]
ReversibleBalancedHuman-GEM MAR02454
H+[c] + linoleate[c] + NADPH[c] + O2[c] = 9(10)-EpOME[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR02455
H+[r] + linoleate[r] + NADPH[r] + O2[r] = 9(10)-EpOME[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR02456
H+[c] + linoleate[c] + NADPH[c] + O2[c] = 12(13)-EpOME[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR02457
H+[r] + linoleate[r] + NADPH[r] + O2[r] = 12(13)-EpOME[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR02458
9(10)-EpOME[c] + H2O[c] = 9,10-hydroxyoctadec-12(Z)-enoate[c]
ReversibleBalancedEC 3.3.2.9, 3.3.2.10Human-GEM MAR02459
9(10)-EpOME[r] + H2O[r] = 9,10-hydroxyoctadec-12(Z)-enoate[r]
ReversibleBalancedEC 3.3.2.9, 3.3.2.10Human-GEM MAR02460
9,10-hydroxyoctadec-12(Z)-enoate[c] + UDP-glucuronate[c] = 9-hydroxy-10-O-D-glucuronoside-(12Z)-octadecenoate[c] + H+[c] + UDP[c]
ReversibleBalancedEC 2.4.1.17Human-GEM MAR02461
9,10-hydroxyoctadec-12(Z)-enoate[r] + UDP-glucuronate[r] = 9-hydroxy-10-O-D-glucuronoside-(12Z)-octadecenoate[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02462
10-hydroxy-octadec-(12Z)-enoate-9-beta-D-glucuronide[c] + H+[c] + UDP[c] = 9,10-hydroxyoctadec-12(Z)-enoate[c] + UDP-glucuronate[c]
ReversibleBalancedEC 2.4.1.17Human-GEM MAR02463
9,10-hydroxyoctadec-12(Z)-enoate[r] + UDP-glucuronate[r] = 10-hydroxy-octadec-(12Z)-enoate-9-beta-D-glucuronide[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02464
12(13)-EpOME[c] + H2O[c] = 12,13-hydroxyoctadec-9(z)-enoate[c]
ReversibleBalancedEC 3.3.2.9, 3.3.2.10Human-GEM MAR02465
12(13)-EpOME[r] + H2O[r] = 12,13-hydroxyoctadec-9(z)-enoate[r]
ReversibleBalancedEC 3.3.2.9, 3.3.2.10Human-GEM MAR02466
12,13-hydroxyoctadec-9(z)-enoate[c] + UDP-glucuronate[c] = 12-hydroxy-13-O-D-glucuronoside-octadec-(9Z)-enoate[c] + H+[c] + UDP[c]
ReversibleBalancedEC 2.4.1.17Human-GEM MAR02467
12,13-hydroxyoctadec-9(z)-enoate[r] + UDP-glucuronate[r] = 12-hydroxy-13-O-D-glucuronoside-octadec-(9Z)-enoate[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02468
12,13-hydroxyoctadec-9(z)-enoate[c] + UDP-glucuronate[c] = 12-O-D-glucuronoside-13-hydroxyoctadec-(9Z)-enoate[c] + H+[c] + UDP[c]
ReversibleBalancedEC 2.4.1.17Human-GEM MAR02469
12,13-hydroxyoctadec-9(z)-enoate[r] + UDP-glucuronate[r] = 12-O-D-glucuronoside-13-hydroxyoctadec-(9Z)-enoate[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02470
9,10-12,13-diepoxy-octadecanoate[c] = 12,13-epoxy-9-alkoxy-(10E)-octadecenoate[c] + H+[c]
Left to rightUnbalancedEC 4.2.1.17Human-GEM MAR03830