Reactions

Reactions

8 reactions in Beta oxidation of unsaturated fatty acids (n-7) (peroxisomal)

• acyl-CoA oxidase ((13Z)-eicosenoyl-CoA)

  (13Z)-eicosenoyl-CoA[x] + FAD[x] = FADH2[x] + trans,cis-2,13-eicosadienoyl-CoA[x]

  → Left to rightBalancedEC 1.3.3.6Human-GEM MAR03356

• enoyl-CoA hydratase (trans,cis-2,13-eicosadienoyl-CoA)

  H2O[x] + trans,cis-2,13-eicosadienoyl-CoA[x] = 3(S)-hydroxy-13-cis-eicosenoyl-CoA[x]

  → Left to rightBalancedEC 4.2.1.17Human-GEM MAR03357

• 3-hydroxyacyl-CoA dehydrogenase (3(S)-hydroxy-13-cis-eicosenoyl-CoA)

  3(S)-hydroxy-13-cis-eicosenoyl-CoA[x] + NAD+[x] = 3-oxo-13-cis-eicosenoyl-CoA[x] + H+[x] + NADH[x]

  → Left to rightBalancedEC 1.1.1.35, 1.1.1.211Human-GEM MAR03358

• acetyl-CoA C-acyltransferase (3-oxo-13-cis-eicosenoyl-CoA)

  3-oxo-13-cis-eicosenoyl-CoA[x] + CoA[x] = acetyl-CoA[x] + cis-vaccenoyl-CoA[x]

  → Left to rightBalancedEC 2.3.1.16Human-GEM MAR03359

• acyl-CoA oxidase (cis-vaccenoyl-CoA)

  cis-vaccenoyl-CoA[x] + FAD[x] = FADH2[x] + trans,cis-octadeca-2,11-dienoyl-CoA[x]