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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

4,901–4,950 of 18,558 reactions from Rhea

holo-[ACP] + acetate + ATP = acetyl-[ACP] + AMP + diphosphate
Direction not assertedBalance undeterminableRhea 31339
(2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + H2O = (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + phosphate
Direction not assertedBalancedRhea 31343
(+)-abscisic acid D-glucopyranosyl ester + H2O = 2-cis-(+)-abscisate + beta-D-glucose + H(+)
Direction not assertedBalancedRhea 31347
lupan-3beta,20-diol = (S)-2,3-epoxysqualene + H2O
Direction not assertedBalancedRhea 31351
dimethyl sulfide + NADH + O2 + H(+) = methanethiol + formaldehyde + NAD(+) + H2O
Direction not assertedBalancedRhea 31355
nitrilotriacetate + FMNH2 + O2 = aminodiacetate + FMN + glyoxylate + H2O
Direction not assertedBalancedRhea 31359
reduced coenzyme F420-(gamma-L-Glu)(n) + NADP(+) = oxidized coenzyme F420-(gamma-L-Glu)(n) + NADPH + 2 H(+)

Direction not assertedBalance undeterminableRhea 31363

3 nitrite + 2 H(+) = 2 nitric oxide + nitrate + H2O

Direction not assertedBalancedRhea 31367

(2R,3S)-2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine = (2R,3S)-2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 31371

pyrrole-2-carboxylate + H(+) = 1H-pyrrole + CO2

Direction not assertedBalancedRhea 31375

pyrrole-2-carboxylate + H2O = 1H-pyrrole + hydrogencarbonate

Direction not assertedBalancedRhea 31379

(S)-2,3-epoxysqualene = lupeol

Direction not assertedBalancedRhea 31383

(S)-2,3-epoxysqualene = alpha-amyrin

Direction not assertedBalancedRhea 31387

15-cis-4,4'-diapophytoene + 4 FAD + 4 H(+) = all-trans-4,4'-diapolycopene + 4 FADH2

Direction not assertedBalancedRhea 31391

15-cis-4,4'-diapophytoene + FAD + H(+) = all-trans-4,4'-diapophytofluene + FADH2

Direction not assertedBalancedRhea 31395

all-trans-4,4'-diapophytofluene + FAD + H(+) = all-trans-4,4'-diapo-zeta-carotene + FADH2

Direction not assertedBalancedRhea 31399

all-trans-4,4'-diapo-zeta-carotene + FAD + H(+) = all-trans-4,4'-diaponeurosporene + FADH2

Direction not assertedBalancedRhea 31403

all-trans-4,4'-diaponeurosporene + FAD + H(+) = all-trans-4,4'-diapolycopene + FADH2

Direction not assertedBalancedRhea 31407

a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 31411

(2Z,6E)-farnesyl diphosphate = (+)-2-epi-prezizaene + diphosphate

Direction not assertedBalancedRhea 31415

(2Z,6E)-farnesyl diphosphate = (-)-beta-curcumene + diphosphate

Direction not assertedBalancedRhea 31419

(2Z,6E)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate

Direction not assertedBalancedRhea 31423

(2E,6E)-farnesyl diphosphate = (1S,5S,6R)-alpha-bergamotene + diphosphate

Direction not assertedBalancedRhea 31427

(2E,6E)-farnesyl diphosphate = (-)-beta-santalene + diphosphate

Direction not assertedBalancedRhea 31431

(2E,6E)-farnesyl diphosphate = (+)-alpha-santalene + diphosphate

Direction not assertedBalancedRhea 31435

(2E,6E)-farnesyl diphosphate = alpha-longipinene + diphosphate

Direction not assertedBalancedRhea 31439

D-sedoheptulose 7-phosphate + ATP = D-sedoheptulose 1,7-bisphosphate + ADP + H(+)

Direction not assertedBalancedRhea 31443

6-amino-2-oxohexanoate + H2O2 = 5-aminopentanoate + CO2 + H2O

Direction not assertedBalancedRhea 31447

2 a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol

Direction not assertedBalance undeterminableRhea 31451

reduced riboflavin + NAD(+) = riboflavin + NADH + 2 H(+)

Direction not assertedBalancedRhea 31455

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate = 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

Direction not assertedBalancedRhea 31459

crocetin + UDP-alpha-D-glucose = beta-D-glucosyl crocetin + UDP

Direction not assertedBalancedRhea 31463

beta-D-glucosyl crocetin + UDP-alpha-D-glucose = bis(beta-D-glucosyl) crocetin + UDP

Direction not assertedBalancedRhea 31467

beta-D-gentiobiosyl crocetin + UDP-alpha-D-glucose = beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP

Direction not assertedBalancedRhea 31471

soyasapogenol B + UDP-alpha-D-glucuronate = soyasapogenol B 3-O-beta-D-glucuronate + UDP + H(+)

Direction not assertedBalancedRhea 31475

soyasapogenol A + UDP-alpha-D-glucuronate = soyasapogenol A 3-O-beta-D-glucuronate + UDP + H(+)

Direction not assertedBalancedRhea 31479

soyasapogenol E + UDP-alpha-D-glucuronate = soyasapogenol E 3-O-beta-D-glucuronate + UDP + H(+)

Direction not assertedBalancedRhea 31483

soyasapogenol B 3-O-beta-D-glucuronate + UDP-alpha-D-galactose = soyasaponin III + UDP + H(+)

Direction not assertedBalancedRhea 31487

soyasaponin III + UDP-beta-L-rhamnose = soyasaponin I + UDP + H(+)

Direction not assertedBalancedRhea 31491

a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 31495

a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc4Cer(d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 31499

beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + phosphoenolpyruvate = 4,6-Me(COOH)C-beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + phosphate

Direction not assertedBalancedRhea 31503

aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + phosphate + 3 H2O + H(+)

Direction not assertedBalancedRhea 31507

chenodeoxycholoyl-CoA + H2O = chenodeoxycholate + CoA + H(+)

Left to rightBalancedRhea 31511

4'-apo-beta-carotenal + NAD(+) + H2O = neurosporaxanthin + NADH + 2 H(+)

Direction not assertedBalancedRhea 31515

torulene + O2 = 4'-apo-beta-carotenal + 3-methyl-2-butenal

Direction not assertedBalancedRhea 31519

2-oxoglutarate + O2 + 2 H(+) = ethene + 3 CO2 + H2O

Direction not assertedBalancedRhea 31523

5-hydroxy-L-arginine = guanidine + L-glutamate 5-semialdehyde

Direction not assertedBalancedRhea 31527

L-arginine + 2-oxoglutarate + O2 = 5-hydroxy-L-arginine + succinate + CO2

Direction not assertedBalancedRhea 31531

L-arginine + 2-oxoglutarate + O2 = guanidine + L-glutamate 5-semialdehyde + succinate + CO2

Direction not assertedBalancedRhea 31535

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