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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

4,851–4,900 of 18,558 reactions from Rhea

5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + diphosphate = 5-amino-4-imidazolecarboxyamide + 5-phospho-alpha-D-ribose 1-diphosphate
Direction not assertedBalancedRhea 31135
(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = 3-hydroxy-3-methyl-2-oxobutanoate + NADPH + H(+)
Direction not assertedBalancedRhea 31139
(3S)-hydroxyhexanoyl-CoA + NAD(+) = 3-oxohexanoyl-CoA + NADH + H(+)
Left to rightBalancedRhea 31143
3,4-dihydroxyphenylethyleneglycol + NAD(+) = 3,4-dihydroxymandelaldehyde + NADH + H(+)
Direction not assertedBalancedRhea 31147
L-selenocystathionine + H2O = L-selenocysteine + 2-oxobutanoate + NH4(+)
Left to rightBalancedRhea 31151
(3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + NAD(+) + 2 H2O = (4S)-4-hydroxy-L-glutamate + NADH + H(+)
Direction not assertedBalancedRhea 31155

(3S)-hydroxyhexadecanoyl-CoA + NAD(+) = 3-oxohexadecanoyl-CoA + NADH + H(+)

ReversibleBalancedRhea 31159

(3S)-hydroxyhexadecanoyl-CoA = (2E)-hexadecenoyl-CoA + H2O

Right to leftBalancedRhea 31163

(3S)-hydroxytetradecanoyl-CoA + NAD(+) = 3-oxotetradecanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 31167

(3S)-hydroxytetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O

Right to leftBalancedRhea 31171

2-methylpropenoyl-CoA + H2O = (S)-3-hydroxyisobutanoyl-CoA

Left to rightBalancedRhea 31175

(3S)-3-hydroxydodecanoyl-CoA + NAD(+) = 3-oxododecanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 31179

decanoyl-CoA + acetyl-CoA = 3-oxododecanoyl-CoA + CoA

Right to leftBalancedRhea 31183

(3S)-hydroxydecanoyl-CoA + NAD(+) = 3-oxodecanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 31187

(3S)-hydroxydecanoyl-CoA = (2E)-decenoyl-CoA + H2O

Right to leftBalancedRhea 31191

(3S)-hydroxyoctanoyl-CoA + NAD(+) = 3-oxooctanoyl-CoA + NADH + H(+)

ReversibleBalancedRhea 31195

(3S)-hydroxyoctanoyl-CoA = (2E)-octenoyl-CoA + H2O

Right to leftBalancedRhea 31199

hexanoyl-CoA + acetyl-CoA = 3-oxooctanoyl-CoA + CoA

Right to leftBalancedRhea 31203

hexanoyl-CoA + FAD + H(+) = (2E)-hexenoyl-CoA + FADH2

Direction not assertedBalancedRhea 31207

L-selenomethionine + ATP + H2O = L-adenosylselenomethionine + phosphate + diphosphate

Direction not assertedBalancedRhea 31211

(5-hydroxyindol-3-yl)acetaldehyde + NAD(+) + H2O = (5-hydroxyindol-3-yl)acetate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31215

5-hydroxykynurenamine + CO2 = 5-hydroxy-L-kynurenine + H(+)

Direction not assertedBalancedRhea 31219

cis-beta-D-glucosyl-2-hydroxycinnamate + H2O = cis-2-coumarate + beta-D-glucose

Direction not assertedBalancedRhea 31223

di-trans,octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans,octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H(+)

Direction not assertedBalancedRhea 31227

4-acetamidobutanal + NAD(+) + H2O = 4-acetamidobutanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31231

(4S)-4-hydroxy-L-glutamate + 2-oxoglutarate = (4R)-4-hydroxy-2-oxoglutarate + L-glutamate

Direction not assertedBalancedRhea 31235

uroporphyrinogen I + 4 H(+) = coproporphyrinogen I + 4 CO2

Left to rightBalancedRhea 31239

L-4-hydroxyglutamate semialdehyde + NAD(+) + H2O = (4S)-4-hydroxy-L-glutamate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31243

prop-2-ynal + pyrroloquinoline quinol + H(+) = prop-2-yn-1-ol + pyrroloquinoline quinone

Direction not assertedBalancedRhea 31247

(S)-3-hydroxyisobutanoyl-CoA + H2O = (S)-3-hydroxy-2-methylpropanoate + CoA + H(+)

Direction not assertedBalancedRhea 31251

(2S)-2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate

Direction not assertedBalancedRhea 31255

but-3-ynal + NAD(+) + H2O = 3-butynoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31259

but-3-ynal + pyrroloquinoline quinol + H(+) = but-3-yn-1-ol + pyrroloquinoline quinone

Direction not assertedBalancedRhea 31263

6-hydroxyhexanoate + NADP(+) = 6-oxohexanoate + NADPH + H(+)

Direction not assertedBalancedRhea 31267

1-hydroxy-2-naphthoate + NADH + O2 + 2 H(+) = naphthalene-1,2-diol + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 31271

(S)-3-hydroxy-2-methylpropanoate + NAD(+) = (S)-2-methyl-3-oxopropanoate + NADH + H(+)

Direction not assertedBalancedRhea 31275

isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = (2Z,6E,10E)-geranylgeranyl diphosphate + diphosphate

Direction not assertedBalancedRhea 31279

sn-glycerol 3-phosphate + FAD + H(+) = dihydroxyacetone phosphate + FADH2

Direction not assertedBalancedRhea 31283

propanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = acryloyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 31287

(2E)-2-hydroxypenta-2,4-dienoate = 2-oxopent-4-enoate

Direction not assertedBalancedRhea 31295

perillyl aldehyde + NAD(+) + H2O = perillate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31299

a reduced flavin + NAD(+) = an oxidized flavin + NADH + 2 H(+)

Direction not assertedBalance undeterminableRhea 31303

an alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = an alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)

Left to rightBalance undeterminableRhea 31307

ADP-alpha-D-glucose + (2R)-3-phosphoglycerate = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + ADP + H(+)

Direction not assertedBalancedRhea 31311

GDP-D-glucose + (2R)-3-phosphoglycerate = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+)

Direction not assertedBalancedRhea 31315

(2R)-3-phosphoglycerate + UDP-alpha-D-glucose = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + UDP + H(+)

Direction not assertedBalancedRhea 31319

(2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP-alpha-D-mannose = (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + GDP + H(+)

Direction not assertedBalancedRhea 31323

CDP-1L-myo-inositol + 1D-myo-inositol 3-phosphate = bis(1L-myo-inositol) 3,1'-phosphate 1-phosphate + CMP + H(+)

Direction not assertedBalancedRhea 31327

molybdopterin + ATP + H(+) = adenylyl-molybdopterin + diphosphate

Left to rightBalancedRhea 31331

Mo-molybdopterin + CTP + H(+) = Mo-molybdopterin cytosine dinucleotide + diphosphate

Direction not assertedBalancedRhea 31335

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