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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
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Chemistry

Reactions
Reach

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Processes
Anatomy
Cell types
Organisms
Materials
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Diseases

Atlas Graph Twin Access

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

4,801–4,850 of 18,558 reactions from Rhea

rhodopin + A = (3E)-3,4-didehydrorhodopin + AH2
Direction not assertedBalancedRhea 30919
ADP-alpha-D-glucose + (R)-glycerate = (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + ADP + H(+)
Direction not assertedBalancedRhea 30923
2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnose + H2O = 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose
Direction not assertedBalancedRhea 30927
O-acetyl-L-homoserine + L-cysteine = L,L-cystathionine + acetate + H(+)
Direction not assertedBalancedRhea 30931
nicotinate beta-D-ribonucleotide + H2O = beta-D-ribosylnicotinate + phosphate
Direction not assertedBalancedRhea 30935
dIDP + ATP = dITP + ADP
Direction not assertedBalancedRhea 30939
octanoyl-CoA + FAD + H(+) = (2E)-octenoyl-CoA + FADH2

Direction not assertedBalancedRhea 30943

(2E,6E)-farnesyl diphosphate + H2O = 10-epi-gamma-eudesmol + diphosphate

Direction not assertedBalancedRhea 30947

(2E,6E)-farnesyl diphosphate + H2O = alpha-eudesmol + diphosphate

Direction not assertedBalancedRhea 30951

9,9'-di-cis-zeta-carotene + 2 a quinone = 7,7',9,9'-tetra-cis-lycopene + 2 a quinol

Direction not assertedBalance undeterminableRhea 30955

9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol

Direction not assertedBalance undeterminableRhea 30959

7,9,9'-tri-cis-neurosporene + a quinone = 7,7',9,9'-tetra-cis-lycopene + a quinol

Direction not assertedBalance undeterminableRhea 30963

9,9',15-tri-cis-zeta-carotene = 9,9'-di-cis-zeta-carotene

Direction not assertedBalancedRhea 30967

7,7',9,9'-tetra-cis-lycopene = all-trans-lycopene

Direction not assertedBalancedRhea 30971

15-cis-phytoene + 5 A = all-trans-3,4-didehydrolycopene + 5 AH2

Direction not assertedBalancedRhea 30975

all-trans-lycopene + A = all-trans-3,4-didehydrolycopene + AH2

Direction not assertedBalancedRhea 30979

a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H2O = beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + L-seryl-[protein]

Direction not assertedBalance undeterminableRhea 30983

(S)-2,3-epoxysqualene = (17Z)-protosta-17(20),24-dien-3beta-ol

Direction not assertedBalancedRhea 30987

beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 24-hydroxy-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 30991

sophoradiol + reduced [NADPH--hemoprotein reductase] + O2 = soyasapogenol B + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 30995

(S)-2,3-epoxysqualene = cucurbitadienol

Direction not assertedBalancedRhea 30999

(S)-2,3-epoxysqualene = germanicol

Direction not assertedBalancedRhea 31003

(S)-2,3-epoxysqualene = beta-amyrin

Direction not assertedBalancedRhea 31007

(S)-2,3-epoxysqualene = camelliol C

Direction not assertedBalancedRhea 31011

indole-3-carboxylate + H(+) = indole + CO2

Direction not assertedBalancedRhea 31015

all-trans-4,4'-diapolycopene + 4 AH2 + 4 O2 = all-trans-4,4'-diapolycopene-4,4'-dial + 4 A + 6 H2O

Direction not assertedBalancedRhea 31019

squalene = dammara-20,24-diene

Direction not assertedBalancedRhea 31023

2-trans-(+)-abscisate + UDP-alpha-D-glucose = beta-D-glucopyranosyl trans-(+)-abscisate + UDP

Direction not assertedBalancedRhea 31027

2-cis-(+)-abscisate + UDP-alpha-D-glucose = beta-D-glucopyranosyl cis-(+)-abscisate + UDP

Direction not assertedBalancedRhea 31031

arabidiol = (S)-2,3-epoxysqualene + H2O

Direction not assertedBalancedRhea 31035

dodecanoyl-CoA + FAD + H(+) = (2E)-dodecenoyl-CoA + FADH2

Direction not assertedBalancedRhea 31039

(S)-2-methyl-3-oxopropanoate + NAD(+) + H2O = methylmalonate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31043

(S)-2-methyl-3-oxopropanoate + NAD(+) + CoA = propanoyl-CoA + CO2 + NADH

Direction not assertedBalancedRhea 31047

(3R)-beta-leucine + NAD(+) + H2O = 4-methyl-3-oxopentanoate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 31051

estrone 3-sulfate + H2O = estrone + sulfate + H(+)

Direction not assertedBalancedRhea 31055

imidazole-4-acetaldehyde + NAD(+) + H2O = imidazole-4-acetate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31059

6-amino-2-oxohexanoate = Delta(1)-piperideine-2-carboxylate + H2O

Direction not assertedBalancedRhea 31067

(S)-2-methyl-3-oxopropanoate + L-alanine = (S)-3-amino-2-methylpropanoate + pyruvate

Direction not assertedBalancedRhea 31071

(3S)-3-hydroxydodecanoyl-CoA = (2E)-dodecenoyl-CoA + H2O

Right to leftBalancedRhea 31075

3-hydroxyisovaleryl-CoA = 3-methylbut-2-enoyl-CoA + H2O

Right to leftBalancedRhea 31079

N-acetyl-D-muramoyl-L-alanine + H2O = N-acetyl-D-muramate + L-alanine

Direction not assertedBalancedRhea 31083

octanoyl-CoA + acetyl-CoA = 3-oxodecanoyl-CoA + CoA

Right to leftBalancedRhea 31087

dodecanoyl-CoA + acetyl-CoA = 3-oxotetradecanoyl-CoA + CoA

Right to leftBalancedRhea 31091

7,8-dihydrofolate + NADP(+) = folate + NADPH + H(+)

Direction not assertedBalancedRhea 31103

3-phenylpyruvate + O2 = (2-hydroxyphenyl)acetate + CO2

Direction not assertedBalancedRhea 31107

butanoyl-CoA + acetyl-CoA = 3-oxohexanoyl-CoA + CoA

Right to leftBalancedRhea 31111

biotin + ATP + H(+) = biotinyl-5'-AMP + diphosphate

Direction not assertedBalancedRhea 31115

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA = (2E)-2-methylbut-2-enoyl-CoA + H2O

Right to leftBalancedRhea 31119

3-O-methylgallate + O2 = 2-oxo-2H-pyran-4,6-dicarboxylate + methanol + H(+)

Direction not assertedBalancedRhea 31127

N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-5,10-methenyltetrahydrofolate + H2O = N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + 2 H(+)

Direction not assertedBalancedRhea 31131

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