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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

4,751–4,800 of 18,558 reactions from Rhea

(2E)-geraniol = (S)-linalool
Direction not assertedBalancedRhea 30715
propanoyl-CoA + acetyl-CoA = 2-methyl-3-oxobutanoyl-CoA + CoA
ReversibleBalancedRhea 30719
A + NH4(+) + 2 ADP + 2 phosphate + H(+) = hydroxylamine + AH2 + 2 ATP + H2O
Direction not assertedBalancedRhea 30723
dATP + pyruvate = dADP + phosphoenolpyruvate + H(+)
Direction not assertedBalancedRhea 30727
butanoyl-CoA + FAD + H(+) = (2E)-butenoyl-CoA + FADH2
Direction not assertedBalancedRhea 30731
1D-myo-inositol 4-phosphate + H2O = myo-inositol + phosphate
Left to rightBalancedRhea 30735
1D-myo-inositol 3-phosphate + H2O = myo-inositol + phosphate
Left to right

→

Balanced

Rhea 30739

beta-nicotinamide D-riboside + H2O = D-ribose + nicotinamide + H(+)

Direction not assertedBalancedRhea 30743

hexadecanoyl-CoA + FAD + H(+) = (2E)-hexadecenoyl-CoA + FADH2

Direction not assertedBalancedRhea 30747

hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 30751

carbamate + ATP = carbamoyl phosphate + ADP

Direction not assertedBalancedRhea 30755

5-methylcytosine + H2O + H(+) = thymine + NH4(+)

Direction not assertedBalancedRhea 30759

L-valine + NAD(+) + H2O = 3-methyl-2-oxobutanoate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 30763

D-glucurono-3,6-lactone + H2O = D-glucuronate + H(+)

Direction not assertedBalancedRhea 30767

guanosine + H2O = guanine + D-ribose

Direction not assertedBalancedRhea 30771

pyridoxamine + O2 + H2O = pyridoxal + H2O2 + NH4(+)

Direction not assertedBalancedRhea 30775

D-gluconate + FAD + H(+) = 2-dehydro-D-gluconate + FADH2

Direction not assertedBalancedRhea 30779

D-glyceraldehyde + NAD(+) + H2O = (R)-glycerate + NADH + 2 H(+)

Direction not assertedBalancedRhea 30783

(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + L-tyrosine + H2O

Direction not assertedBalancedRhea 30787

dGTP + pyruvate = dGDP + phosphoenolpyruvate + H(+)

Direction not assertedBalancedRhea 30791

2-oxoadipate + NAD(+) + CoA = glutaryl-CoA + CO2 + NADH

Direction not assertedBalancedRhea 30795

(3S)-3-hydroxybutanoyl-CoA + NAD(+) = acetoacetyl-CoA + NADH + H(+)

ReversibleBalancedRhea 30799

4-aminobutanal + NADP(+) + H2O = 4-aminobutanoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 30803

L-pipecolate + NAD(+) = Delta(1)-piperideine-2-carboxylate + NADH + H(+)

Right to leftBalancedRhea 30807

beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinamide D-riboside + phosphate

Direction not assertedBalancedRhea 30815

allantoin + H2O = allantoate + H(+)

Direction not assertedBalancedRhea 30819

UDP-N-acetyl-alpha-D-glucosamine = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H2O

Direction not assertedBalancedRhea 30823

UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose = UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose

Direction not assertedBalancedRhea 30827

UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose = UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-hex-4-ulose

Direction not assertedBalancedRhea 30831

UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + NADPH + H(+) = UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP(+)

Direction not assertedBalancedRhea 30835

UDP-2-acetamido-2,6-dideoxy-beta-L-talose = UDP-N-acetyl-beta-L-fucosamine

Direction not assertedBalancedRhea 30839

N-formylmaleamate + H2O = maleamate + formate + H(+)

Direction not assertedBalancedRhea 30843

glutaryl-CoA + FAD + 2 H(+) = (2E)-butenoyl-CoA + FADH2 + CO2

Direction not assertedBalancedRhea 30847

beta-D-fructose 1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate

ReversibleBalancedRhea 30851

dammarenediol-II = (S)-2,3-epoxysqualene + H2O

Direction not assertedBalancedRhea 30855

dITP + H2O = dIDP + phosphate + H(+)

Direction not assertedBalancedRhea 30859

4-O-phospho-L-tyrosine + H2O = L-tyrosine + phosphate

Direction not assertedBalancedRhea 30863

indole-3-acetaldehyde + NAD(+) + H2O = (indol-3-yl)acetate + NADH + 2 H(+)

Direction not assertedBalancedRhea 30867

2-deoxy-D-ribose + ATP = 2-deoxy-D-ribose 5-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 30871

D-lysine + 2-oxoglutarate = 6-amino-2-oxohexanoate + D-glutamate

Direction not assertedBalancedRhea 30875

prop-2-ynal + NAD(+) + H2O = propynoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 30879

D-glucurono-3,6-lactone + NAD(+) + 2 H2O = D-glucarate + NADH + 3 H(+)

Direction not assertedBalancedRhea 30883

6-hydroxymethyl-7,8-dihydropterin + 4-aminobenzoate = 7,8-dihydropteroate + H2O

Direction not assertedBalancedRhea 30887

O-acetyl-L-serine + thiosulfate = S-sulfo-L-cysteine + acetate + H(+)

Direction not assertedBalancedRhea 30891

propane-1,3-diamine + O2 + H2O = 3-aminopropanal + H2O2 + NH4(+)

Direction not assertedBalancedRhea 30895

bis(beta-D-glucosyl) crocetin + UDP-alpha-D-glucose = beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP + H(+)

Direction not assertedBalancedRhea 30899

demethylspheroidene + S-adenosyl-L-methionine = spheroidene + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 30903

(S)-3-methyl-2-oxopentanoate + NAD(+) + CoA = (2S)-2-methylbutanoyl-CoA + CO2 + NADH

Direction not assertedBalancedRhea 30907

a sphingomyelin + H2O = sphing-4-enine-phosphocholine + a carboxylate

Direction not assertedBalance undeterminableRhea 30911

a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = beta-D-glucosyl-(1<->1)-sphing-4-enine + a fatty acid

Left to rightBalance undeterminableRhea 30915

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