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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

4,551–4,600 of 18,558 reactions from Rhea

L-ornithine(out) + ATP + H2O = L-ornithine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29883
L-lysine(out) + ATP + H2O = L-lysine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29887
L-histidine(out) + ATP + H2O = L-histidine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29891
L-glutamine(out) + ATP + H2O = L-glutamine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29895
D-xylose(out) + ATP + H2O = D-xylose(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29899
D-ribose(out) + ATP + H2O = D-ribose(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29903

sn-glycero-3-phospho-(1'-rac-glycerol) + H2O = sn-glycerol 3-phosphate + glycerol + H(+)

Direction not assertedBalancedRhea 29907

L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + UDP-alpha-D-glucose = alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP + H(+)

Direction not assertedBalancedRhea 29915

alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP = alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalancedRhea 29919

alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP-L-glycero-beta-D-manno-heptose = alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalancedRhea 29923

(R)-pantothenate(in) + Na(+)(in) = (R)-pantothenate(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 29927

alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP = alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalancedRhea 29931

cytosine(in) + H(+)(in) = cytosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29935

phosphate(in) + H(+)(in) = phosphate(out) + H(+)(out)

Right to leftBalancedTransportRhea 29939

2-dehydro-3-deoxy-D-gluconate(in) + H(+)(in) = 2-dehydro-3-deoxy-D-gluconate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29943

L-rhamnopyranose(in) + H(+)(in) = L-rhamnopyranose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29947

uridine(in) + H(+)(in) = uridine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29951

thymidine(in) + H(+)(in) = thymidine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29955

alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP-alpha-D-galactose = alpha-D-Gal-(1->6)-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP + H(+)

Direction not assertedBalancedRhea 29959

inosine(in) + H(+)(in) = inosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29963

2'-deoxyuridine(in) + H(+)(in) = 2'-deoxyuridine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29967

2'-deoxyinosine(in) + H(+)(in) = 2'-deoxyinosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29971

2'-deoxycytidine(in) + H(+)(in) = 2'-deoxycytidine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29975

2'-deoxyadenosine(in) + H(+)(in) = 2'-deoxyadenosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29979

cytidine(in) + H(+)(in) = cytidine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29983

adenosine(in) + H(+)(in) = adenosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29987

L-lyxopyranose(in) + H(+)(in) = L-lyxopyranose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29991

putrescine(out) + ATP + H2O = putrescine(in) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 29995

spermidine(out) + ATP + H2O = spermidine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29999

alpha-D-Gal-(1->6)-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP-alpha-D-glucose = alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP + H(+)

Direction not assertedBalancedRhea 30003

L-arabinose(out) + ATP + H2O = L-arabinose(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 30007

beta-D-galactose(out) + ATP + H2O = beta-D-galactose(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 30011

alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP-alpha-D-glucose = alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP + H(+)

Direction not assertedBalancedRhea 30015

alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H(+)

Direction not assertedBalancedRhea 30019

pyridoxal 5'-phosphate + L-alanine = pyridoxamine 5'-phosphate + pyruvate

Direction not assertedBalancedRhea 30023

D-glyceraldehyde + NADH + H(+) = glycerol + NAD(+)

Direction not assertedBalancedRhea 30027

(S)-muconolactone = cis,cis-muconate + H(+)

Direction not assertedBalancedRhea 30031

3,4-dihydroxybenzoate + NADH + O2 + 2 H(+) = benzene-1,2,4-triol + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 30035

3,4-dihydroxybenzoate + NADPH + O2 + 2 H(+) = benzene-1,2,4-triol + CO2 + NADP(+) + H2O

Direction not assertedBalancedRhea 30039

fumarate + L-aspartate = iminosuccinate + succinate

Direction not assertedBalancedRhea 30043

chloroacetaldehyde + NAD(+) + H2O = chloroacetate + NADH + 2 H(+)

Direction not assertedBalancedRhea 30047

fluoroacetate + H2O = fluoride + glycolate + H(+)

Direction not assertedBalancedRhea 30051

L-allo-threonine + NADP(+) = (2S)-2-amino-3-oxobutanoate + NADPH + H(+)

Direction not assertedBalancedRhea 30055

(S)-dihydroorotate + fumarate = orotate + succinate

Direction not assertedBalancedRhea 30059

2-demethylmenaquinol-8 + S-adenosyl-L-methionine = menaquinol-8 + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 30063

betaine aldehyde + NADP(+) + H2O = glycine betaine + NADPH + 2 H(+)

Direction not assertedBalancedRhea 30067

butanoate + acetyl-CoA = butanoyl-CoA + acetate

Direction not assertedBalancedRhea 30071

CMP + H2O = cytosine + D-ribose 5-phosphate

Direction not assertedBalancedRhea 30075

crotonobetaine + ATP + CoA = crotonobetainyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 30079

4 Cu(+) + O2 + 4 H(+) = 4 Cu(2+) + 2 H2O

Left to rightBalancedRhea 30083

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