Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

4,301–4,350 of 18,558 reactions from Rhea

Ag(+)(in) + H(+)(in) = Ag(+)(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28859
lactose(in) + H(+)(out) = lactose(out) + H(+)(in)
Direction not assertedBalancedTransportRhea 28863
lactose(in) + H(+)(in) = lactose(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28867
D-fructuronate(in) + H(+)(in) = D-fructuronate(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28871
L-tyrosine(in) + H(+)(in) = L-tyrosine(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28875
L-tryptophan(in) + H(+)(in) = L-tryptophan(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28879
L-threonine(in) + H(+)(in) = L-threonine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28883

L-serine(in) + H(+)(in) = L-serine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28887

putrescine(in) + H(+)(in) = putrescine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28891

cadaverine(in) + L-lysine(out) = cadaverine(out) + L-lysine(in)

Direction not assertedBalancedTransportRhea 28895

glycine(in) + H(+)(in) = glycine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28899

D-alanine(in) + H(+)(in) = D-alanine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28903

3-(3-hydroxyphenyl)propanoate(in) + H(+)(in) = 3-(3-hydroxyphenyl)propanoate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28907

L-lysine(out) + H(+)(out) = L-lysine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 28911

4-aminobutanoate(in) + H(+)(in) = 4-aminobutanoate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28915

4-aminobutanoate(in) + L-glutamate(out) = 4-aminobutanoate(out) + L-glutamate(in)

Direction not assertedBalancedTransportRhea 28919

L-phenylalanine(in) + H(+)(in) = L-phenylalanine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28923

3,4,5-trihydroxybenzoate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + 2 H(+)

Direction not assertedBalancedRhea 28927

(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate = 4-carboxy-2-hydroxy-cis,cis-muconate

Direction not assertedBalancedRhea 28931

2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = oxaloacetate + pyruvate

Direction not assertedBalancedRhea 28935

xanthosine(in) + H(+)(in) = xanthosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28939

glycine betaine(in) = glycine betaine(out)

Direction not assertedBalancedTransportRhea 28943

L-arabinose(in) + H(+)(out) = L-arabinose(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28947

L-arabinose(in) + H(+)(in) = L-arabinose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28951

aldehydo-D-glucuronate(in) + H(+)(in) = aldehydo-D-glucuronate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28955

D-xylose(in) + H(+)(in) = D-xylose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28959

L-proline(out) + H(+)(out) = L-proline(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 28963

L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)

Right to leftBalancedTransportRhea 28967

shikimate(in) + H(+)(in) = shikimate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28971

L-asparagine(in) + H(+)(out) = L-asparagine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28975

nitrite(in) + H(+)(out) = nitrite(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28979

nitrite(in) = nitrite(out)

Direction not assertedBalancedTransportRhea 28983

N-acetylneuraminate(in) + H(+)(in) = N-acetylneuraminate(out) + H(+)(out)

Right to leftBalancedTransportRhea 28987

N-acetylneuraminate(in) = N-acetylneuraminate(out)

Direction not assertedBalancedTransportRhea 28991

L-threonine(in) + H(+)(out) = L-threonine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28995

homoserine lactone(in) + H(+)(out) = homoserine lactone(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28999

L-homoserine(in) + H(+)(out) = L-homoserine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 29003

Mn(2+)(in) + H(+)(in) = Mn(2+)(out) + H(+)(out)

ReversibleBalancedTransportRhea 29007

2-oxoglutarate(in) + H(+)(in) = 2-oxoglutarate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29011

sn-glycerol 3-phosphate(in) + phosphate(out) = sn-glycerol 3-phosphate(out) + phosphate(in)

Direction not assertedBalancedTransportRhea 29015

D-galactose(in) + H(+)(in) = D-galactose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29019

L-fucose(in) + H(+)(in) = L-fucose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29023

L-glutamate(in) + 2 H(+)(in) = L-glutamate(out) + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29027

L-glutamate(in) + 2 Na(+)(in) = L-glutamate(out) + 2 Na(+)(out)

Direction not assertedBalancedTransportRhea 29031

L-glutamate(out) + ATP + H2O = L-glutamate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29035

L-aspartate(out) + ATP + H2O = L-aspartate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29039

dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H(+) = dTMP + (6S)-5,6,7,8-tetrahydrofolate + NADP(+)

Direction not assertedBalancedRhea 29043

H2 + a menaquinone + 2 H(+)(in) = a menaquinol + 2 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 29047

menaquinone-8 + H2 + 2 H(+)(in) = menaquinol-8 + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29051

H2 + a ubiquinone + 2 H(+)(in) = a ubiquinol + 2 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 29055

Page 87 of 372