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Evidence

CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

351–400 of 18,558 reactions from Rhea

a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)
Direction not assertedBalance undeterminableRhea 11484
all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA
Left to rightBalance undeterminableRhea 11488
O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO2
Direction not assertedBalancedRhea 11492
O-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate + H(+)
Direction not assertedBalancedRhea 11496
3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + H2O = 3-deoxy-alpha-D-manno-oct-2-ulosonate + phosphate
Direction not assertedBalancedRhea 11500
6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 11504

L-aspartyl-[protein] + 2-oxoglutarate + O2 = 3-hydroxy-L-aspartyl-[protein] + succinate + CO2

Direction not assertedBalance undeterminableRhea 11508

salicyl alcohol + UDP-alpha-D-glucose = salicin + UDP + H(+)

Direction not assertedBalancedRhea 11512

succinyl-CoA + H2O = succinate + CoA + H(+)

Left to rightBalancedRhea 11516

(-)-menthol + UDP-alpha-D-glucose = (-)-menthyl beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 11520

5beta-cholestan-3-one + NADP(+) = cholest-4-en-3-one + NADPH + H(+)

Right to leftBalancedRhea 11524

2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] + 2 ATP = 2 adenosylcob(III)yrinate a,c-diamide + 2 triphosphate + oxidized [electron-transfer flavoprotein] + 3 H(+)

Direction not assertedBalance undeterminableRhea 11528

glycine + O2 + H2O = glyoxylate + H2O2 + NH4(+)

Direction not assertedBalancedRhea 11532

choline + 2 O2 + H2O = glycine betaine + 2 H2O2 + H(+)

Direction not assertedBalancedRhea 11536

an N-acyl-D-mannosamine + NAD(+) = an N-acyl-D-mannosaminolactone + NADH + H(+)

Direction not assertedBalance undeterminableRhea 11540

N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+)

Direction not assertedBalancedRhea 11544

5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+)

Direction not assertedBalancedRhea 11548

a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)

Left to rightBalance undeterminableRhea 11552

(S)-carnitine + NAD(+) = 3-dehydrocarnitine + NADH + H(+)

Direction not assertedBalancedRhea 11556

(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) = catechol + CO2 + NADH

Direction not assertedBalancedRhea 11560

4-O-beta-D-glucopyranosyl-D-gluconate + phosphate = D-gluconate + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 11564

dCMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 5-methyldeoxycytidine 5'-phosphate + 7,8-dihydrofolate

Direction not assertedBalancedRhea 11568

lithocholate + FAD + H2O + H(+) = chenodeoxycholate + FADH2

Direction not assertedBalancedRhea 11572

thiamine + ATP = thiamine diphosphate + AMP + H(+)

Direction not assertedBalancedRhea 11576

a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)

ReversibleBalance undeterminableRhea 11580

L-ornithine = D-ornithine

Direction not assertedBalancedRhea 11584

isoquinoline + A + H2O = isoquinolin-1(2H)-one + AH2

Direction not assertedBalancedRhea 11588

dihydromonacolin L-[lovastatin nonaketide synthase] + H2O = holo-[lovastatin nonaketide synthase] + dihydromonacolin L carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 11592

orotidine 5'-phosphate + H(+) = UMP + CO2

Left to rightBalancedRhea 11596

CMP + ATP = CDP + ADP

Direction not assertedBalancedRhea 11600

[N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA = [O(7),N-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA

Direction not assertedBalance undeterminableRhea 11604

[N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA = [N,O(9)-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA

Direction not assertedBalance undeterminableRhea 11608

L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+)

Direction not assertedBalancedRhea 11612

L-2-amino-4-chloropent-4-enoate + H2O = 2-oxopent-4-enoate + chloride + NH4(+) + H(+)

Direction not assertedBalancedRhea 11620

2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate

Direction not assertedBalancedRhea 11624

a 2-oxocarboxylate + H(+) = an aldehyde + CO2

Direction not assertedBalance undeterminableRhea 11628

L-selenocysteine + AH2 = hydrogenselenide + L-alanine + A + H(+)

Left to rightBalancedRhea 11632

prostaglandin E1 + NADP(+) = 15-oxoprostaglandin E1 + NADPH + H(+)

Left to rightBalancedRhea 11636

a (2R,3R)-flavan-3-ol + 2 NAD(+) = an anthocyanidin with a 3-hydroxy group + 2 NADH + 2 H(+)

Direction not assertedBalance undeterminableRhea 11640

a (2R,3R)-flavan-3-ol + 2 NADP(+) = an anthocyanidin with a 3-hydroxy group + 2 NADPH + 2 H(+)

Direction not assertedBalance undeterminableRhea 11644

(-)-menthol + NADPH + O2 + H(+) = 1,4-menthane-3,8-diol + NADP(+) + H2O

Direction not assertedBalancedRhea 11648

di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-galactose = alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP

Direction not assertedBalancedRhea 11652

holo-[peptidyl-carrier protein] + L-proline + ATP = L-prolyl-[peptidyl-carrier protein] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 11656

a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + acetate

Left to rightBalance undeterminableRhea 11660

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + CMP-N-acetyl-beta-neuraminate = a 1,2-diacyl-3-[3-(N-acetyl-alpha-D-neuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+)

Direction not assertedBalance undeterminableRhea 11664

[(1->4)-alpha-D-glucosyl](n) + n ATP + n H2O = [(1->4)-6-phospho-alpha-D-glucosyl](n) + n AMP + n phosphate + 2n H(+)

Direction not assertedBalance undeterminableRhea 11668

chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate

Direction not assertedBalancedRhea 11672

D-ribose + NADP(+) + H2O = D-ribonate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 11676

XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)

Left to rightBalancedRhea 11680

methylarsonous acid + S-adenosyl-L-methionine = dimethylarsinate + S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 11684

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