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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

3,751–3,800 of 18,558 reactions from Rhea

(1S,5R)-carveol + NAD(+) = (R)-carvone + NADH + H(+)
Direction not assertedBalancedRhea 25844
(1S,5S)-carveol + NAD(+) = (S)-carvone + NADH + H(+)
Direction not assertedBalancedRhea 25848
an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an (11Z)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Direction not assertedBalance undeterminableRhea 25852
(9Z)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Direction not assertedBalance undeterminableRhea 25856
GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + formate + diphosphate + H(+)
Direction not assertedBalancedRhea 25860
N(1)-acetylspermidine + O2 + H2O = 4-acetamidobutanal + propane-1,3-diamine + H2O2
Direction not assertedBalancedRhea 25864

N(1),N(12)-diacetylspermine + O2 + H2O = 3-acetamidopropanal + N(1)-acetylspermidine + H2O2

Direction not assertedBalancedRhea 25868

pyridine + H2O2 = pyridine N-oxide + H2O

Direction not assertedBalancedRhea 25872

L-aspartate + O2 = iminosuccinate + H2O2

Direction not assertedBalancedRhea 25876

2 L-dopa + O2 = 2 3-(3,4-dihydroxyphenyl)pyruvate + 2 NH4(+)

Direction not assertedBalancedRhea 25880

N(2)-succinyl-L-ornithine + carbamoyl phosphate = N(2)-succinyl-L-citrulline + phosphate + H(+)

Direction not assertedBalancedRhea 25884

iminosuccinate + dihydroxyacetone phosphate = quinolinate + phosphate + 2 H2O + H(+)

Direction not assertedBalancedRhea 25888

malonate + H(+) = acetate + CO2

Direction not assertedBalancedRhea 25896

D-arabino-hex-3-ulose 6-phosphate = beta-D-fructose 6-phosphate

Direction not assertedBalancedRhea 25900

futalosine + H2O = dehypoxanthine futalosine + hypoxanthine

Direction not assertedBalancedRhea 25904

an alditol + O2 = an aldose + H2O2

Direction not assertedBalance undeterminableRhea 25908

quinolin-5-ol + A + H2O = 5-hydroxyquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25912

quinolin-6-ol + A + H2O = 6-hydroxyquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25916

quinolin-7-ol + A + H2O = 7-hydroxyquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25920

quinolin-8-ol + A + H2O = 8-hydroxyquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25924

3-methylquinoline + A + H2O = 3-methylquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25928

4-methylquinoline + A + H2O = 4-methylquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25932

8-methylquinoline + A + H2O = 8-methylquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25936

8-chloroquinoline + A + H2O = 8-chloroquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25940

a 1,2-diacyl-sn-glycerol + CTP = a 1,2-diacyl-sn-glycero-3-phosphate + CDP + H(+)

Direction not assertedBalance undeterminableRhea 25948

1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + L-aspartate 4-semialdehyde = 2,3-dioxopropyl phosphate + 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate

Direction not assertedBalancedRhea 25952

2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + NAD(+) + H2O = 3-dehydroquinate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 25956

benzoin + NADP(+) = benzil + NADPH + H(+)

Direction not assertedBalancedRhea 25960

(R)-benzoin + NADP(+) = benzil + NADPH + H(+)

Direction not assertedBalancedRhea 25964

(S)-benzoin + NADP(+) = benzil + NADPH + H(+)

Direction not assertedBalancedRhea 25968

N(8)-acetylspermidine + O2 + H2O = 4-acetamidobutanal + propane-1,3-diamine + H2O2

Direction not assertedBalancedRhea 25972

(+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (5S)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 25976

(5S)-albaflavenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = albaflavenone + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 25980

(+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (5R)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 25984

(5R)-albaflavenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = albaflavenone + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 25988

(2E,6E)-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate

Direction not assertedBalancedRhea 25992

N(1)-acetylspermine + O2 + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + H2O2

Direction not assertedBalancedRhea 25996

D-arabinitol 1-phosphate + NAD(+) = D-xylulose 5-phosphate + NADH + H(+)

Direction not assertedBalancedRhea 26002

di-trans,nona-cis-dodecaprenyl phosphate + UDP-alpha-D-galacturonate = beta-D-galacturonosyl di-trans,nona-cis-dodecaprenyl phosphate + UDP

Direction not assertedBalancedRhea 26006

2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + NAD(+) + H2O = 3,7-dideoxy-D-threo-hepto-2,6-diuolosonate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 26010

3,7-dideoxy-D-threo-hepto-2,6-diuolosonate = 3-dehydroquinate

Direction not assertedBalancedRhea 26014

beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + H2O = beta-D-fructofuranosyl alpha-D-mannopyranoside + phosphate

Direction not assertedBalancedRhea 26019

8'-apo-beta-carotenol + O2 = 14'-apo-beta-carotenal + (3E,5E)-7-hydroxy-6-methylhepta-3,5-dienal

Direction not assertedBalancedRhea 26023

N(1)-acetylspermidine + O2 + H2O = N-acetylputrescine + 3-aminopropanal + H2O2

Direction not assertedBalancedRhea 26027

2 flaviolin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = 3,3'-biflaviolin + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 26031

2 flaviolin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = 3,8'-biflaviolin + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 26035

beta-D-fructose 6-phosphate + GDP-alpha-D-mannose = beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + GDP + H(+)

Direction not assertedBalancedRhea 26039

(6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced [NADPH--hemoprotein reductase] + O2 = glyceollin II + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 26047

(6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced [NADPH--hemoprotein reductase] + O2 = glyceollin III + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 26051

valienol 1-phosphate + GTP + H(+) = GDP-valienol + diphosphate

Direction not assertedBalancedRhea 26055

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