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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
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Chemistry

Reactions
Reach

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Processes
Anatomy
Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

3,701–3,750 of 18,558 reactions from Rhea

sulfoacetaldehyde + NAD(+) + H2O = sulfoacetate + NADH + 2 H(+)
Direction not assertedBalancedRhea 25637
(1R,4S)-menthone + NADP(+) = (R)-pulegone + NADPH + H(+)
Direction not assertedBalancedRhea 25641
(2R,5R)-isomenthone + NADP(+) = (R)-pulegone + NADPH + H(+)
Direction not assertedBalancedRhea 25645
(2R,5R)-isopulegone + NADP(+) = (6R)-isopiperitenone + NADPH + H(+)
Direction not assertedBalancedRhea 25649
(2S)-2-amino-3-oxobutanoate + H(+) = aminoacetone + CO2
Direction not assertedBalancedRhea 25653
(R)-pulegone + reduced [NADPH--hemoprotein reductase] + O2 = (R)-menthofuran + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Direction not assertedBalance undeterminableRhea 25658
(2E)-geranyl diphosphate = alpha-pinene + diphosphate

Direction not assertedBalancedRhea 25662

(2E)-geranyl diphosphate = beta-pinene + diphosphate

Direction not assertedBalancedRhea 25666

sucrose + UDP-alpha-D-galactose = loliose + UDP + H(+)

Direction not assertedBalancedRhea 25670

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate

Direction not assertedBalance undeterminableRhea 25674

tRNA(Cys) + O-phospho-L-serine + ATP = O-phospho-L-seryl-tRNA(Cys) + AMP + diphosphate

Direction not assertedBalancedRhea 25678

L-dihomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 25682

O-phospho-L-seryl-tRNA(Cys) + hydrogen sulfide + H(+) = L-cysteinyl-tRNA(Cys) + phosphate

Direction not assertedBalancedRhea 25686

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + CTP + H(+) = CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + diphosphate

Direction not assertedBalancedRhea 25690

isopentenyl diphosphate + (2E,6E,10E)-geranylgeranyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate

Direction not assertedBalancedRhea 25694

N,N-dihydroxy-L-hexahomomethionine + H(+) = (E)-9-(methylsulfanyl)nonanal oxime + CO2 + H2O

Direction not assertedBalancedRhea 25698

N-hydroxy-L-dihomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 25702

N,N-dihydroxy-L-dihomomethionine + H(+) = (E)-5-(methylsulfanyl)pentanal oxime + CO2 + H2O

Direction not assertedBalancedRhea 25706

L-trihomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 25711

N-hydroxy-L-trihomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 25715

N,N-dihydroxy-L-trihomomethionine + H(+) = (E)-6-(methylsulfanyl)hexanal oxime + CO2 + H2O

Direction not assertedBalancedRhea 25719

L-tetrahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-tetrahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 25723

N-hydroxy-L-tetrahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-tetrahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 25727

N,N-dihydroxy-L-tetrahomomethionine + H(+) = (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O

Direction not assertedBalancedRhea 25731

L-pentahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 25735

N-hydroxy-L-pentahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 25739

N,N-dihydroxy-L-pentahomomethionine + H(+) = (E)-8-(methylsulfanyl)octanal oxime + CO2 + H2O

Direction not assertedBalancedRhea 25743

L-hexahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 25747

N-hydroxy-L-hexahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 25751

ent-copalyl diphosphate = ent-isokaurene + diphosphate

Direction not assertedBalancedRhea 25759

(2R,3S)-3-methylmalate + NAD(+) = 3-carboxy-2-oxobutanoate + NADH + H(+)

Direction not assertedBalancedRhea 25763

3-carboxy-2-oxobutanoate + H(+) = 2-oxobutanoate + CO2

Direction not assertedBalancedRhea 25767

L-asparagine + 2-oxoglutarate + O2 = (2S,3S)-3-hydroxyasparagine + succinate + CO2

Direction not assertedBalancedRhea 25772

scyllo-inosose = scyllo-inosine

Direction not assertedBalancedRhea 25776

UDP-N-acetyl-alpha-D-mannosamine + 2 NAD(+) + H2O = UDP-N-acetyl-alpha-D-mannosaminouronate + 2 NADH + 3 H(+)

Direction not assertedBalancedRhea 25780

2-dehydro-3-deoxy-L-rhamnonate = (S)-lactaldehyde + pyruvate

Direction not assertedBalancedRhea 25784

4-hydroxy-2-oxoheptanedioate = succinate semialdehyde + pyruvate

Direction not assertedBalancedRhea 25788

Cu(+)(in) + ATP + H2O = Cu(+)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 25792

L-methionine + 2-oxoglutarate = 4-methylsulfanyl-2-oxobutanoate + L-glutamate

Direction not assertedBalancedRhea 25796

N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2

Direction not assertedBalancedRhea 25800

spermine + O2 + H2O = 3-aminopropanal + spermidine + H2O2

Direction not assertedBalancedRhea 25804

spermidine + O2 + H2O = 3-aminopropanal + putrescine + H2O2

Direction not assertedBalancedRhea 25808

N(1)-acetylspermidine + O2 + H2O = 3-acetamidopropanal + putrescine + H2O2

Direction not assertedBalancedRhea 25812

norspermine + O2 + H2O = norspermidine + 3-aminopropanal + H2O2

Direction not assertedBalancedRhea 25816

spermidine + O2 + H2O = 4-aminobutanal + propane-1,3-diamine + H2O2

Direction not assertedBalancedRhea 25820

spermine + O2 + H2O = N-(3-aminopropyl)-4-aminobutanal + propane-1,3-diamine + H2O2

Direction not assertedBalancedRhea 25824

an N-acyl-(4R)-4-hydroxysphinganine + AH2 + O2 = a (4R,8E)-4-hydroxysphingenine ceramide + A + 2 H2O

Direction not assertedBalance undeterminableRhea 25828

1D-chiro-inositol + NAD(+) = scyllo-inosine + NADH + H(+)

Direction not assertedBalancedRhea 25832

3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O = 5-deoxy-D-glucuronate + H(+)

Direction not assertedBalancedRhea 25836

5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate

Direction not assertedBalancedRhea 25840

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