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3,401–3,450 of 12,877 reactions from Human-GEM
ATP[x] + CoA[x] + (3R)-phytanic acid[x] = AMP[x] + (3R)-phytanoyl-CoA[x] + PPi[x]
Left to rightBalancedEC 6.2.1.24Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03482
3-oxo-all-cis-6,9,12,15,18-tetracosapentaenoyl-CoA[x] + CoA[x] + 2 H+[x] = (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA[x] + acetyl-CoA[x]
ReversibleUnbalancedEC 2.3.1.16Fatty acid oxidationHuman-GEM MAR03483
AKG[x] + O2[x] + (3R)-phytanoyl-CoA[x] = (3R)-2-hydroxyphytanoyl-CoA[x] + CO2[x] + succinate[x]
Left to rightBalancedEC 1.14.11.18Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03484
H+[r] + linoleoyl-CoA[r] + malonyl-CoA[r] = 3-oxoeicosa-cis,cis-11,14-dienoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 2.3.1.199Fatty acid oxidation
(3R)-2-hydroxyphytanoyl-CoA[x] = formyl-CoA[x] + (2R)-pristanal[x]
Left to rightBalancedEC 4.1.-.-Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03486
3-oxoeicosa-cis,cis-11,14-dienoyl-CoA[r] + H+[r] + NADPH[r] = (3S)-hydroxy-eicosa-cis,cis-11,14-dienoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03487
H2O[x] + NAD+[x] + (2R)-pristanal[x] = (2R)-pristanic acid[x] + 2 H+[x] + NADH[x]
Left to rightBalancedEC 1.14.11.18Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03488
(3S)-hydroxy-eicosa-cis,cis-11,14-dienoyl-CoA[r] = H2O[r] + trans,cis,cis-2,11,14-eicosatrienoyl-CoA[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03490
(2R)-pristanoyl-CoA[x] = (2S)-pristanoyl-CoA[x]
ReversibleBalancedEC 5.1.99.4Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03491
H+[r] + NADPH[r] + trans,cis,cis-2,11,14-eicosatrienoyl-CoA[r] = (11Z,14Z)-eicosadienoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03492
(2R)-pristanic acid[x] + ATP[x] + CoA[x] = (2R)-pristanoyl-CoA[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.-Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03493
dihomo-gamma-linolenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-oxo-docosa-cis,cis,cis-10,13,16-trienoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03494
3-oxo-docosa-cis,cis,cis-10,13,16-trienoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-10,13,16-all-cis-docosatrienoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 6.2.1.3Fatty acid oxidationHuman-GEM MAR03495
3(S)-hydroxy-10,13,16-all-cis-docosatrienoyl-CoA[r] = H2O[r] + trans,cis,cis,cis-2,10,13,16-docosatetraenoyl-CoA[r]
ReversibleBalancedEC 1.3.1.70Fatty acid oxidationHuman-GEM MAR03496
H+[r] + NADPH[r] + trans,cis,cis,cis-2,10,13,16-docosatetraenoyl-CoA[r] = 10,13,16-docosatrienoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.16Fatty acid oxidationHuman-GEM MAR03497
(2S)-pristanoyl-CoA[x] + FAD[x] = FADH2[x] + trans-2,3-dehydropristanoyl-CoA[x]
Left to rightBalancedEC 1.3.3.6Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03498
H+[r] + NADPH[r] + trans,cis,cis,cis,cis-2,10,13,16,19-docosapentaenoyl-CoA[r] = 10,13,16,19-docosatetraenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 1.1.1.35Fatty acid oxidationHuman-GEM MAR03499
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-oxo-docosa-10,13,16,19-all-cis-tetraenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03500
H2O[x] + trans-2,3-dehydropristanoyl-CoA[x] = 3-hydroxypristanoyl-CoA[x]
Left to rightBalancedEC 4.2.1.17Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03501
3-oxo-docosa-10,13,16,19-all-cis-tetraenoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-docosa-10,13,16,19-all-cis-tetraenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 6.2.1.3Fatty acid oxidationHuman-GEM MAR03502
3-hydroxypristanoyl-CoA[x] + NAD+[x] = 3-ketopristanoyl-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03503
3(S)-hydroxy-docosa-10,13,16,19-all-cis-tetraenoyl-CoA[r] = H2O[r] + trans,cis,cis,cis,cis-2,10,13,16,19-docosapentaenoyl-CoA[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03504
3-ketopristanoyl-CoA[x] + CoA[x] = 4,8,12-trimethyltridecanoyl-CoA[x] + propanoyl-CoA[x]
Left to rightBalancedEC 2.3.1.176Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03505
4,8,12-trimethyltridecanoyl-CoA[x] + FAD[x] = (4R,8R,12R)-trimethyl-(2E)-tridecenoyl-CoA[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03506
H+[r] + NADPH[r] + trans,cis,cis,cis,cis-2,12,15,18,21-tetracosapentaenoyl-CoA[r] = 12,15,18,21-tetracosatetraenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03507
(4R,8R,12R)-trimethyl-(2E)-tridecenoyl-CoA[x] + H2O[x] = 3(R)-hydroxy-(4R,8R,12R)-trimethyl-tridecanoyl-CoA[x]
Left to rightBalancedEC 4.2.1.17Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03508
3(R)-hydroxy-(4R,8R,12R)-trimethyl-tridecanoyl-CoA[x] + NAD+[x] = 3-oxo-(4R,8R,12R)-trimethyl-tridecanoyl-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03509
3-oxo-(4R,8R,12R)-trimethyl-tridecanoyl-CoA[x] + CoA[x] = (2R,6R,10R)-trimethyl-hendecanoyl-CoA[x] + acetyl-CoA[x]
Left to rightBalancedEC 2.3.1.16Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03510
(2R,6R,10R)-trimethyl-hendecanoyl-CoA[x] = (2S,6R,10R)-trimethyl-hendecanoyl-CoA[x]
Left to rightBalancedEC 5.1.99.4Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03511
(2S,6R,10R)-trimethyl-hendecanoyl-CoA[x] + FAD[x] = (2S,6R,10R)-trimethyl-(2E)-hendecenoyl-CoA[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03512
(2S,6R,10R)-trimethyl-(2E)-hendecenoyl-CoA[x] + H2O[x] = 3(R)-hydroxy-(2S,6R,10)-trimethyl-hendecanoyl-CoA[x]
Left to rightBalancedEC 4.2.1.17Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03513
3(R)-hydroxy-(2S,6R,10)-trimethyl-hendecanoyl-CoA[x] + NAD+[x] = 3-oxo-(2S,6R,10R)-trimethyl-hendecanoyl-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03514
3-oxo-(2S,6R,10R)-trimethyl-hendecanoyl-CoA[x] + CoA[x] = 4(R),8-dimethyl-nonanoyl-CoA[x] + propanoyl-CoA[x]
Left to rightBalancedEC 2.3.1.176Beta oxidation of phytanic acid (peroxisomal)Human-GEM MAR03515
10,13,16,19-docosatetraenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-oxo-tetracosa-12,15,18,21-all-cis-tetraenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03516
4(R),8-dimethyl-nonanoyl-CoA[c] = 4(R),8-dimethyl-nonanoyl-CoA[x]
ReversibleBalancedTransportEC 1.5.1.10Transport reactionsHuman-GEM MAR03517
3-oxo-tetracosa-12,15,18,21-all-cis-tetraenoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-tetracosa-12,15,18,21-all-cis-tetraenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03518
4(R),8-dimethyl-nonanoyl-CoA[m] + L-carnitine[m] = 4,8-dimethylnonanoylcarnitine[m] + CoA[m]
ReversibleBalancedCarnitine shuttle (mitochondrial)Human-GEM MAR03519
4,8-dimethylnonanoylcarnitine[c] + L-carnitine[m] = 4,8-dimethylnonanoylcarnitine[m] + L-carnitine[c]
ReversibleBalancedTransportCarnitine shuttle (mitochondrial)Human-GEM MAR03520
4(R),8-dimethyl-nonanoyl-CoA[c] + L-carnitine[c] = 4,8-dimethylnonanoylcarnitine[c] + CoA[c]
ReversibleBalancedCarnitine shuttle (cytosolic)Human-GEM MAR03521
4(R),8-dimethyl-nonanoyl-CoA[m] + FAD[m] = 4(R),8-dimethyl-trans-2-nonenoyl-CoA[m] + FADH2[m]
Left to rightBalancedEC 1.3.8.7, 1.3.8.8Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03522
4(R),8-dimethyl-trans-2-nonenoyl-CoA[m] + H2O[m] = 3(S)-hydroxy-4(R),8-dimethyl-nonanoyl-CoA[m]
Left to rightBalancedEC 4.2.1.17Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03523
3(S)-hydroxy-4(R),8-dimethyl-nonanoyl-CoA[m] + NAD+[m] = 3-oxo-4(R),8-dimethyl-nonanoyl-CoA[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03524
3-oxo-4(R),8-dimethyl-nonanoyl-CoA[m] + CoA[m] = 2(R),6-dimethyl-heptanoyl-CoA[m] + acetyl-CoA[m]
Left to rightBalancedEC 2.3.1.16, 1.1.1.211Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03525
2(R),6-dimethyl-heptanoyl-CoA[m] = 2(S),6-dimethyl-heptanoyl-CoA[m]
Left to rightBalancedEC 5.1.99.4Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03526
2(S),6-dimethyl-heptanoyl-CoA[m] + FAD[m] = 2,6-dimethyl-trans-2-heptenoyl-CoA[m] + FADH2[m]
Left to rightBalancedEC 1.3.8.7, 1.3.8.8Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03527
2,6-dimethyl-trans-2-heptenoyl-CoA[m] + H2O[m] = 3(S)-hydroxy-2(S),6-dimethyl-heptanoyl-CoA[m]
Left to rightBalancedEC 4.2.1.17Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03528
3(S)-hydroxy-2(S),6-dimethyl-heptanoyl-CoA[m] + NAD+[m] = 3-oxo-(2S)-methylisocapryloyl-CoA[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03529
3-oxo-(2S)-methylisocapryloyl-CoA[m] + CoA[m] = 4-methyl-pentanoyl-CoA[m] + propanoyl-CoA[m]
Left to rightBalancedEC 2.3.1.16, 1.1.1.211Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03530
4-methyl-pentanoyl-CoA[m] + FAD[m] = 4-methyl-trans-2-pentenoyl-CoA[m] + FADH2[m]
Left to rightBalancedEC 1.3.8.7, 1.3.8.8Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03531
4-methyl-trans-2-pentenoyl-CoA[m] + H2O[m] = 3(S)-hydroxy-4-methyl-pentanoyl-CoA[m]
Left to rightBalancedEC 4.2.1.17Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03532