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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

3,351–3,400 of 18,558 reactions from Rhea

sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate
Direction not assertedBalancedRhea 24048
a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + oxidized [electron-transfer flavoprotein] + H(+)
Left to rightBalance undeterminableRhea 24052
a myo-inositol phosphate + H2O = myo-inositol + phosphate
Left to rightBalancedRhea 24056
N-hydroxy-L-tyrosine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 24060
2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)
Direction not assertedBalancedRhea 24064
cyclohexanone + NADPH + O2 + H(+) = hexano-6-lactone + NADP(+) + H2O
Direction not assertedBalancedRhea 24068
a 3beta-hydroxy-Delta(5)-steroid + NAD(+) = a 3-oxo-Delta(5)-steroid + NADH + H(+)

Direction not assertedBalance undeterminableRhea 24076

tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)

Left to rightBalancedRhea 24080

all-trans-zeaxanthin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = all-trans-antheraxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 24084

2 sulochrin + O2 + 2 H(+) = 2 (2S)-bisdechlorogeodin + 2 H2O

Direction not assertedBalancedRhea 24092

isoorientin + S-adenosyl-L-methionine = isoscoparin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 24096

diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H(+)

Direction not assertedBalancedRhea 24100

7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine

Direction not assertedBalancedRhea 24104

N-methyl-2-oxoglutaramate + H2O = methylamine + 2-oxoglutarate

Direction not assertedBalancedRhea 24108

2 glutathione + O2 = glutathione disulfide + H2O2

Direction not assertedBalancedRhea 24112

(2E)-geranyl diphosphate + H2O = (S)-linalool + diphosphate

Direction not assertedBalancedRhea 24116

leukotriene E4 + NADPH + O2 + H(+) = 20-hydroxy-leukotriene E4 + NADP(+) + H2O

Direction not assertedBalancedRhea 24120

UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose

Direction not assertedBalancedRhea 24132

a primary amine + 3'-phosphoadenylyl sulfate = a sulfamate + adenosine 3',5'-bisphosphate + 2 H(+)

Direction not assertedBalance undeterminableRhea 24136

guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2251) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 24140

3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O

Direction not assertedBalancedRhea 24144

D-glyceraldehyde 3-phosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = (2R)-3-phosphoglycerate + 2 reduced [2Fe-2S]-[ferredoxin] + 3 H(+)

Direction not assertedBalance undeterminableRhea 24148

adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)

Left to rightBalancedRhea 24152

2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP

Direction not assertedBalancedRhea 24156

D-galactose + O2 = D-galacto-hexodialdose + H2O2

Direction not assertedBalancedRhea 24160

L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol

Direction not assertedBalance undeterminableRhea 24164

3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 24168

a 3-oxo-5beta-steroid + A = a 3-oxo-Delta(4)-steroid + AH2

Direction not assertedBalance undeterminableRhea 24172

[ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + a uridine in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + ATP + H(+) = [ThiI sulfur-carrier protein]-L-cysteine + a 4-thiouridine in tRNA + 2 oxidized [2Fe-2S]-[ferredoxin] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 24176

2-hydroxyisobutanoyl-CoA + L-lysyl-[protein] = N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + CoA + H(+)

Left to rightBalance undeterminableRhea 24180

4,5-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO2

Direction not assertedBalancedRhea 24184

cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + NADH + H(+)

Direction not assertedBalancedRhea 24188

(2R,4S)-2,4-diaminopentanoate + NADP(+) + H2O = (2R)-2-amino-4-oxopentanoate + NH4(+) + NADPH + H(+)

Direction not assertedBalancedRhea 24192

(2R,4S)-2,4-diaminopentanoate + NAD(+) + H2O = (2R)-2-amino-4-oxopentanoate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 24196

4-aminobenzoate + H(+) = aniline + CO2

Direction not assertedBalancedRhea 24200

acetyl phosphate + sulfite + H(+) = sulfoacetaldehyde + phosphate

Direction not assertedBalancedRhea 24204

1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH + H(+)

Direction not assertedBalancedRhea 24208

5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)

Direction not assertedBalancedRhea 24212

(2E,6E)-farnesal + NAD(+) + H2O = (2E,6E)-farnesoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 24216

beta-myrcene + reduced [NADPH--hemoprotein reductase] + O2 = (4R)-ipsdienol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 24220

(1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NADP(+) = 4-methylcatechol + CO2 + NADPH

Direction not assertedBalancedRhea 24224

(1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NAD(+) = 4-methylcatechol + CO2 + NADH

Direction not assertedBalancedRhea 24228

2-dehydro-3-deoxy-D-gluconate + NAD(+) = 3-deoxy-D-glycero-2,5-hexodiulosonate + NADH + H(+)

Direction not assertedBalancedRhea 24232

trimethylamine + 2 Fe(III)-[cytochrome c] + H2O = trimethylamine N-oxide + 2 Fe(II)-[cytochrome c] + 3 H(+)

Direction not assertedBalance undeterminableRhea 24236

sulfite + A + AMP + 2 H(+) = adenosine 5'-phosphosulfate + AH2

Direction not assertedBalancedRhea 24240

pseudotropine + NADP(+) = tropinone + NADPH + H(+)

Direction not assertedBalancedRhea 24244

glyoxylate + L-alanine = glycine + pyruvate

Left to rightBalancedRhea 24248

P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP + 2 H(+)

Direction not assertedBalancedRhea 24252

kanamycin A + ATP = kanamycin 3'-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 24256

(3E)-2-oxohex-3-enedioate + H(+) = 2-oxopent-4-enoate + CO2

Direction not assertedBalancedRhea 24260

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