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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

3,201–3,250 of 18,558 reactions from Rhea

alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate
Direction not assertedBalancedRhea 23424
3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)
Left to rightBalance undeterminableRhea 23428
(4S)-limonene + reduced [NADPH--hemoprotein reductase] + O2 = (4S)-perillyl alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 23432
2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate
Direction not assertedBalancedRhea 23436
4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H(+)
Direction not assertedBalancedRhea 23440
(S)-lactate + NAD(+) = pyruvate + NADH + H(+)
Reversible

Balanced

Rhea 23444

3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate

Direction not assertedBalancedRhea 23448

2'-deoxyadenosine + ATP = dAMP + ADP + H(+)

Direction not assertedBalancedRhea 23452

(9Z,12Z)-octadecadienoate + AH2 + O2 = crepenynate + A + 2 H2O

Direction not assertedBalancedRhea 23456

benzyl cetraxate + H2O = cetraxate + benzyl alcohol + H(+)

Direction not assertedBalancedRhea 23460

3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 23464

2-aminobenzenesulfonate + NADH + O2 + 2 H(+) = 2,3-dihydroxybenzenesulfonate + NH4(+) + NAD(+)

Direction not assertedBalancedRhea 23468

2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose

Direction not assertedBalancedRhea 23472

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O

Direction not assertedBalancedRhea 23476

2-methylene-3-methylsuccinate = dimethylmaleate

Direction not assertedBalancedRhea 23480

D-cellobiose + A = D-cellobiono-1,5-lactone + AH2

Direction not assertedBalancedRhea 23484

1,4-benzoquinone + NADPH + H(+) = hydroquinone + NADP(+)

Direction not assertedBalancedRhea 23488

UDP-alpha-D-glucosamine = UDP-alpha-D-galactosamine

Direction not assertedBalancedRhea 23492

5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate

Direction not assertedBalancedRhea 23496

N(6)-propanoyl-L-lysyl-[protein] + NAD(+) + H2O = 3''-O-propanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 23500

adenosylcob(III)inamide + H2O = (R)-1-aminopropan-2-ol + adenosylcob(III)yrate

Direction not assertedBalancedRhea 23504

(7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate

Direction not assertedBalancedRhea 23508

alpha,alpha-trehalose + phosphate = beta-D-glucose 1-phosphate + D-glucose

Direction not assertedBalancedRhea 23512

(R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+)

Direction not assertedBalancedRhea 23516

propanoate + acetyl-CoA = propanoyl-CoA + acetate

Direction not assertedBalancedRhea 23520

1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol = an alkyl cinnamate + beta-D-glucose

Direction not assertedBalance undeterminableRhea 23524

cholate + ATP + CoA = choloyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 23532

alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate

Direction not assertedBalancedRhea 23536

tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate

Left to rightBalancedRhea 23540

a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-alpha-D-glucose = a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP + H(+)

Direction not assertedBalance undeterminableRhea 23544

guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 23548

2-methylpropane-1,2-diol + NAD(+) = 2-hydroxy-2-methylpropanal + NADH + H(+)

Direction not assertedBalancedRhea 23552

D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH4(+)

Direction not assertedBalancedRhea 23556

alpha-ribazole 5'-phosphate + adenosylcob(III)inamide-GDP = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)

Direction not assertedBalancedRhea 23560

2 columbamine + O2 = 2 berberine + 2 H2O

Direction not assertedBalancedRhea 23564

(2E)-decenoyl-[ACP] = (3Z)-decenoyl-[ACP]

Direction not assertedBalance undeterminableRhea 23568

3-methylbutanoyl-CoA + 3 malonyl-CoA + 3 H(+) = phlorisovalerophenone + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 23572

(R)-N-methylcoclaurine + (S)-N-methylcoclaurine + reduced [NADPH--hemoprotein reductase] + O2 = berbamunine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 23576

prostaglandin H2 = prostaglandin I2

Left to rightBalancedRhea 23580

7,8-dihydropteroate + L-glutamate + ATP = 7,8-dihydrofolate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 23584

oxalate + succinyl-CoA = oxalyl-CoA + succinate

Direction not assertedBalancedRhea 23588

glycerol + NADP(+) = D-glyceraldehyde + NADPH + H(+)

Direction not assertedBalancedRhea 23592

UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)

Direction not assertedBalancedRhea 23596

L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate

Direction not assertedBalancedRhea 23600

kievitone hydrate = kievitone + H2O

Direction not assertedBalancedRhea 23604

N-isopropylammelide + H2O + H(+) = isopropylamine + cyanurate

Direction not assertedBalancedRhea 23608

1,2-dihydro-alpha-santonin + NAD(+) = alpha-santonin + NADH + H(+)

Direction not assertedBalancedRhea 23612

1,2-dihydro-alpha-santonin + NADP(+) = alpha-santonin + NADPH + H(+)

Direction not assertedBalancedRhea 23616

N(2)-(2-carboxyethyl)-L-arginine + ATP = deoxyamidinoproclavaminate + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 23620

a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 23624

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