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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

3,051–3,100 of 18,558 reactions from Rhea

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methenyltetrahydrofolate + NADPH
Left to rightBalancedRhea 22812
alpha-D-xylose = alpha-D-xylulofuranose
Direction not assertedBalancedRhea 22816
3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+)
Direction not assertedBalance undeterminableRhea 22820
2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil
Left to rightBalancedRhea 22824
1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)
Direction not assertedBalancedRhea 22828
N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH4(+)
Direction not assertedBalancedRhea 22832

a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 22836

D-glutamine + H2O = D-glutamate + NH4(+)

Direction not assertedBalancedRhea 22840

(6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced [NADPH--hemoprotein reductase] + O2 = glyceollin I + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 22844

(3S)-hydroxyoctanedioyl-CoA + NAD(+) = 3-oxooctanedioyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 22848

L-serine + pyruvate = 3-hydroxypyruvate + L-alanine

Left to rightBalancedRhea 22852

(7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA

Direction not assertedBalancedRhea 22856

nicotinate beta-D-ribonucleotide + ATP + H(+) = deamido-NAD(+) + diphosphate

ReversibleBalancedRhea 22860

L-lysine = D-lysine

Direction not assertedBalancedRhea 22864

thioglycolate + 3-chloro-L-alanine = S-carboxymethyl-L-cysteine + chloride + H(+)

Direction not assertedBalancedRhea 22868

L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-3-hydroxy-L-prolyl-[collagen] + succinate + CO2

Left to rightBalance undeterminableRhea 22872

(R)-mandelamide + H2O = (R)-mandelate + NH4(+)

Direction not assertedBalancedRhea 22876

L-arogenate + 2-oxoglutarate = prephenate + L-glutamate

Direction not assertedBalancedRhea 22880

glyoxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + glycine

Direction not assertedBalancedRhea 22884

(R)-methylmalonyl-CoA = succinyl-CoA

Left to rightBalancedRhea 22888

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methenyltetrahydrofolate + NADH

Direction not assertedBalancedRhea 22892

n malonyl-CoA + acetyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acyl-CoA + n CO2 + 2n NADP(+) + n CoA + H2O

Direction not assertedBalance undeterminableRhea 22896

(R)-acetoin + NAD(+) = diacetyl + NADH + H(+)

Direction not assertedBalancedRhea 22900

ent-7alpha-hydroxykaur-16-en-19-oate + reduced [NADPH--hemoprotein reductase] + O2 = gibberellin A12 aldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 22904

3',5'-cyclic AMP + H2O + H(+) = 3',5'-cyclic IMP + NH4(+)

Direction not assertedBalancedRhea 22908

L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine

Direction not assertedBalancedRhea 22912

4'-hydroxyacetophenone + NADPH + O2 + H(+) = 4-acetoxyphenol + NADP(+) + H2O

Direction not assertedBalancedRhea 22916

scyllo-inosose + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate

Direction not assertedBalancedRhea 22920

dCMP + H2O + H(+) = dUMP + NH4(+)

Left to rightBalancedRhea 22924

4-acetamidobutanoyl-CoA + H2O = 4-aminobutanoyl-CoA + acetate

Direction not assertedBalancedRhea 22928

an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)

Left to rightBalance undeterminableRhea 22932

N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate

Direction not assertedBalancedRhea 22936

L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + H(+)

Direction not assertedBalancedRhea 22940

3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + NADPH + H(+)

Right to leftBalancedRhea 22944

D-tagatofuranose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate

Direction not assertedBalancedRhea 22948

octanedioyl-CoA + O2 = (2E)-octenedioyl-CoA + H2O2

Direction not assertedBalancedRhea 22952

a 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Left to rightBalance undeterminableRhea 22956

formononetin + reduced [NADPH--hemoprotein reductase] + O2 = calycosin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 22960

L-ornithine + H(+) = putrescine + CO2

Direction not assertedBalancedRhea 22964

butanal + NAD(+) + CoA = butanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 22968

butanal + NADP(+) + CoA = butanoyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 22972

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + ATP + CoA = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 22976

a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 22980

oxamate + carbamoyl phosphate = N-carbamoyl-2-oxoglycine + phosphate

Direction not assertedBalancedRhea 22984

3-oxopropanoate + NADP(+) + CoA = acetyl-CoA + CO2 + NADPH

Direction not assertedBalancedRhea 22988

3-oxopropanoate + NAD(+) + CoA = acetyl-CoA + CO2 + NADH

Direction not assertedBalancedRhea 22992

L-ascorbate + H2O2 = L-dehydroascorbate + 2 H2O

Direction not assertedBalancedRhea 22996

(R)-pantoate + NAD(+) = (R)-4-dehydropantoate + NADH + H(+)

Direction not assertedBalancedRhea 23000

a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 23004

alpha,alpha-trehalose 6-phosphate + H2O = D-glucose 6-phosphate + D-glucose

Direction not assertedBalancedRhea 23008

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