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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

26,701–26,750 of 31,435, by identifier

2 Fe(III)-[cytochrome c] + NADPH = 2 Fe(II)-[cytochrome c] + NADP(+) + H(+)
Direction not assertedBalance undeterminableRhea 67656
an (11Z)-eicosenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a (8Z,11Z)-eicosadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O
Direction not assertedBalance undeterminableRhea 67660
[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine-N-glycine + [protein]-C-terminal L-amino acid
Direction not assertedBalance undeterminableRhea 67664
a 1-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine
Direction not assertedBalance undeterminableRhea 67668
a 1,2-diacyl-sn-glycero-3-phosphate + a 1-acyl-sn-glycero-3-phosphocholine = a 1-acyl-sn-glycero-3-phosphate + a 1,2-diacyl-sn-glycero-3-phosphocholine
Direction not assertedBalance undeterminableRhea 67672
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 67676

a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)

Left to rightBalance undeterminableRhea 67680

a long-chain fatty acid(in) + ATP + H2O = a long-chain fatty acid(out) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 67684

2,6,10,14-tetramethylpentadecanoate(in) + ATP + H2O = 2,6,10,14-tetramethylpentadecanoate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 67688

hexadecanedioate(in) + ATP + H2O = hexadecanedioate(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 67692

hexadecanedioyl-CoA + H2O = hexadecanedioate + CoA + H(+)

Left to rightBalancedRhea 67696

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + CoA + H(+)

Left to rightBalancedRhea 67700

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(in) + ATP + H2O = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 67704

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(in) + ATP + H2O = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 67708

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + CoA + H(+)

Left to rightBalancedRhea 67712

2 oxidized [2Fe-2S]-[protein] + NADPH = 2 reduced [2Fe-2S]-[protein] + NADP(+) + H(+)

Left to rightBalance undeterminableRhea 67716

chloromethane + H2O = methanol + chloride + H(+)

Direction not assertedBalancedRhea 67720

CMP-N-acetyl-beta-neuraminate(in) + CMP(out) = CMP-N-acetyl-beta-neuraminate(out) + CMP(in)

Direction not assertedBalancedTransportRhea 67724

dZTP + DNA(n) = DNA(n)-Z + diphosphate

Direction not assertedBalance undeterminableRhea 67728

uridylyl-uridylyl-ribonucleotide-RNA = a 3'-end uridylyl-2',3'-cyclophospho-uridine-RNA + a 5'-end dephospho-ribonucleoside-RNA

Direction not assertedBalance undeterminableRhea 67732

N-acetyl-alpha-neuraminate = aceneuramate

Direction not assertedBalancedRhea 67736

N-acetyl-beta-neuraminate = aceneuramate

Direction not assertedBalancedRhea 67740

1-O-alkyl-2-acyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) + H2O = 1-O-alkyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + phosphate

Direction not assertedBalance undeterminableRhea 67744

a 1-acyl-sn-glycero-3-phosphate + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate

ReversibleBalance undeterminableRhea 67748

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)

ReversibleBalancedRhea 67752

1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine

Direction not assertedBalancedRhea 67756

1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho]-glycerol + 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine = 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol

Direction not assertedBalancedRhea 67760

1',3'-bis[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

Direction not assertedBalancedRhea 67764

1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol

Direction not assertedBalancedRhea 67768

a 5'-end 5'-phospho-ribonucleoside-RNA + H2O = a 5'-end dephospho-ribonucleoside-RNA + phosphate

Direction not assertedBalance undeterminableRhea 67772

a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H2O = a 5'-end dephospho-2'-deoxyribonucleoside-DNA + phosphate

Direction not assertedBalance undeterminableRhea 67776

1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho]-glycerol + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol

Direction not assertedBalancedRhea 67780

2 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol = 1',3'-bis-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + 1',3'-bis[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol

Direction not assertedBalancedRhea 67784

2 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol = 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + a cardiolipin

Direction not assertedBalance undeterminableRhea 67788

ribonucleotidyl-uridine-RNA = a 5'-end dephospho-uridine-RNA + a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA

Left to rightBalance undeterminableRhea 67792

a ribonucleotidyl-ribonucleotide-RNA = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA

Left to rightBalance undeterminableRhea 67796

N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2

Left to rightBalance undeterminableRhea 67800

N(6)-methyl-L-lysyl(20)-[histone H4] + 2-oxoglutarate + O2 = L-lysyl(20)-[histone H4] + formaldehyde + succinate + CO2

Left to rightBalance undeterminableRhea 67804

L-lysyl(8)-[histone H2AZ] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(8)-[histone H2AZ] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 67808

a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]

Direction not assertedBalance undeterminableRhea 67812

a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate

Direction not assertedBalance undeterminableRhea 67816

1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine = 1-(9Z-hexadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol

Direction not assertedBalancedRhea 67820

a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H2O = a lipid X + UMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 67824

a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + UDP + H(+)

Direction not assertedBalance undeterminableRhea 67828

N(6)-methyl-L-lysyl(27)-[histone H3] + 2-oxoglutarate + O2 = L-lysyl(27)-[histone H3] + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 67832

1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

Direction not assertedBalancedRhea 67836

a lipid A disaccharide + ATP = a lipid IVA + ADP + H(+)

Direction not assertedBalance undeterminableRhea 67840

a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)

Direction not assertedBalance undeterminableRhea 67844

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ATP + CoA = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 67848

FMNH2 + O2 = FMN-N(5)-peroxide

Direction not assertedBalancedRhea 67852

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