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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

26,451–26,500 of 31,435, by identifier

(2E,6E)-farnesyl diphosphate + H2O = trichobrasilenol + diphosphate
Direction not assertedBalancedRhea 66644
(2E,6E)-farnesyl diphosphate = african-3-ene + diphosphate
Direction not assertedBalancedRhea 66648
(2E,6E)-farnesyl diphosphate = african-1-ene + diphosphate
Direction not assertedBalancedRhea 66652
Cu(2+)(out) + L-ascorbate(in) = Cu(+)(out) + monodehydro-L-ascorbate radical(in) + H(+)
Direction not assertedBalancedRhea 66656
a beta-D-glucosylceramide(in) + ATP + H2O = a beta-D-glucosylceramide(out) + ADP + phosphate + H(+)
Left to rightBalance undeterminableTransportRhea 66660
coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 66664
5-methylorsellinate + reduced [NADPH--hemoprotein reductase] + O2 = 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 66668

4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) = 5,7-dihydroxy-4-methylphthalide + H2O

Direction not assertedBalancedRhea 66672

5,7-dihydroxy-4-methylphthalide + (2E,6E)-farnesyl diphosphate = 4-farnesyl-3,5-dihydroxy-6-methylphthalide + diphosphate

Direction not assertedBalancedRhea 66676

coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66680

S-nitroso-L-cysteinyl-[GAPDH] + L-cysteinyl-[protein] = L-cysteinyl-[GAPDH] + S-nitroso-L-cysteinyl-[protein]

Left to rightBalance undeterminableRhea 66684

4-farnesyl-3,5-dihydroxy-6-methylphthalide + AH2 + 2 O2 = (4E,8E)-10-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + acetone + A + H2O + H(+)

Direction not assertedBalancedRhea 66688

dTDP-beta-L-rhamnose + L-arginyl-[protein] = N(omega)-(alpha-L-rhamnosyl)-L-arginyl-[protein] + dTDP + H(+)

Direction not assertedBalance undeterminableRhea 66692

(4E,8E)-10-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + S-adenosyl-L-methionine = (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 66696

(4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + ATP + CoA = (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 66700

mycophenolyl-CoA + H2O = mycophenolate + CoA + H(+)

Direction not assertedBalancedRhea 66704

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + hexadecanoate + H(+)

Left to rightBalancedRhea 66708

stellata-2,6,19-triene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = stellatate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 66712

6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde 3-phosphate = D-fructose 6-phosphate + (2S)-3-sulfolactaldehyde

Direction not assertedBalancedRhea 66716

N-[(S)-lactoyl]-L-phenylalanine(in) + ATP + H2O = N-[(S)-lactoyl]-L-phenylalanine(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66720

(S)-lactate + L-phenylalanine = N-[(S)-lactoyl]-L-phenylalanine + H2O

ReversibleBalancedRhea 66724

N-acetyl-L-aspartyl-L-glutamate(in) + ATP + H2O = N-acetyl-L-aspartyl-L-glutamate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66728

N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(in) + ATP + H2O = N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66732

beta-citrylglutamate(in) + ATP + H2O = beta-citrylglutamate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66736

N-acetyl-L-glutamate(in) + ATP + H2O = N-acetyl-L-glutamate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66740

N-acetyl-L-aspartate(in) + ATP + H2O = N-acetyl-L-aspartate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66744

(2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(in) + ATP + H2O = (2S)-2-[5-amino-1-(beta-D-ribosyl)imidazole-4-carboxamido]succinate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66752

domoate(in) + ATP + H2O = domoate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66756

kainate(in) + ATP + H2O = kainate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66760

folate(in) + ATP + H2O = folate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66764

coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66768

uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66772

uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66776

6-phospho-N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine + H2O = N-acetyl-D-muramate 6-phosphate + N-acetyl-D-glucosamine

Direction not assertedBalancedRhea 66780

N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine(out) + N(pros)-phospho-L-histidyl-[protein] = 6-phospho-N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine(in) + L-histidyl-[protein]

Direction not assertedBalance undeterminableRhea 66784

N-methyl-L-dopa + O2 = (3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2

Direction not assertedBalancedRhea 66788

N-methyl-D-dopa + O2 = (3R)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2

Direction not assertedBalancedRhea 66792

miltiradiene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = 11-oxomiltiradiene + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 66796

miltiradiene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = miltiradien-20-al + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 66800

ferruginol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = pisiferate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 66804

5-aminopentanoate + 7 malonyl-CoA + acetyl-CoA + 11 NADPH + 17 H(+) = wortmanamide A + 7 CO2 + 11 NADP(+) + 8 CoA + 6 H2O

Direction not assertedBalancedRhea 66808

5-aminopentanoate + 8 malonyl-CoA + acetyl-CoA + 13 NADPH + 20 H(+) = wortmanamide B + 8 CO2 + 13 NADP(+) + 9 CoA + 7 H2O

Direction not assertedBalancedRhea 66812

tetrahydroxoborate(in) + 2 Na(+)(in) = tetrahydroxoborate(out) + 2 Na(+)(out)

Left to rightBalancedTransportRhea 66816

Mn(2+)(in) + ATP + H2O = Mn(2+)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66820

2 cob(II)inamide + reduced [electron-transfer flavoprotein] + 2 ATP + 2 H2O = 2 adenosylcob(III)inamide + oxidized [electron-transfer flavoprotein] + 2 phosphate + 2 diphosphate + 3 H(+)

Direction not assertedBalance undeterminableRhea 66824

2 cob(II)alamin + reduced [electron-transfer flavoprotein] + 2 ATP + 2 H2O = 2 adenosylcob(III)alamin + oxidized [electron-transfer flavoprotein] + 2 phosphate + 2 diphosphate + 3 H(+)

Direction not assertedBalance undeterminableRhea 66828

(2E,6E,10E,14E)-geranylfarnesyl diphosphate = preasperterpenoid A + diphosphate

Direction not assertedBalancedRhea 66832

preasperterpenoid A + 4 reduced [NADPH--hemoprotein reductase] + 4 O2 = asperterpenoid A + 4 oxidized [NADPH--hemoprotein reductase] + 5 H2O + 5 H(+)

Direction not assertedBalance undeterminableRhea 66836

asperterpenoid A + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = asperterpenoid B + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 3 H(+)

Direction not assertedBalance undeterminableRhea 66840

asperterpenoid A + reduced [NADPH--hemoprotein reductase] + O2 = asperterpenoid C + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 66844

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