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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

25,001–25,050 of 31,435, by identifier

P(1),P(2)-bis(5'-adenosyl) diphosphate + H2O = 2 AMP + 2 H(+)
Direction not assertedBalancedRhea 60824
a 5'-end triphospho-adenosine in mRNA + H2O = a 5'-end diphospho-adenosine in mRNA + phosphate + H(+)
Direction not assertedBalance undeterminableRhea 60828
a 5'-end triphospho-guanosine in mRNA + H2O = a 5'-end diphospho-guanosine in mRNA + phosphate + H(+)
Direction not assertedBalance undeterminableRhea 60832
a 5'-end diphospho-adenosine in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + diphosphate
Direction not assertedBalance undeterminableRhea 60836
a 5'-end diphospho-adenosine in mRNA + N(epsilon)-GMP-L-lysyl-[protein] + 2 H(+) = a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + L-lysyl-[protein]
Direction not assertedBalance undeterminableRhea 60840
a 5'-end diphospho-guanosine in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + diphosphate
Direction not asserted

Balance undeterminable

Rhea 60844

a 5'-end diphospho-guanosine in mRNA + N(epsilon)-GMP-L-lysyl-[protein] + 2 H(+) = a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + L-lysyl-[protein]

Direction not assertedBalance undeterminableRhea 60848

a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 60852

a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 60856

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-adenosine) in mRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 60860

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-guanosine) in mRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 60864

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + H2O = a 5'-end phospho-adenosine in mRNA + N(7)-methyl-GDP + 2 H(+)

Direction not assertedBalance undeterminableRhea 60868

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O = a 5'-end phospho-guanosine in mRNA + N(7)-methyl-GDP + 2 H(+)

Direction not assertedBalance undeterminableRhea 60872

a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)

Left to rightBalance undeterminableRhea 60876

a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)

Left to rightBalance undeterminableRhea 60880

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine-phospho-ribonucleoside in mRNA + H2O = (N(7)-methyl 5'-triphospho-guanosine)-adenosine + a 5'-end phospho-ribonucleoside in mRNA + H(+)

Direction not assertedBalance undeterminableRhea 60884

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine-phospho-ribonucleoside in mRNA + H2O = (N(7)-methyl 5'-triphospho-guanosine)-guanosine + a 5'-end phospho-ribonucleoside in mRNA + H(+)

Direction not assertedBalance undeterminableRhea 60888

a 5'-end NAD(+)-phospho-ribonucleoside in snoRNA + H2O = a 5'-end phospho-ribonucleoside in snoRNA + NAD(+) + H(+)

Left to rightBalance undeterminableRhea 60892

a 2-acyl-6-(alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 60896

a cytidine in RNA + S-adenosyl-L-methionine = an N(3)-methylcytidine in RNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 60900

(9Z,12Z,15Z)-octadecatrienoate + O2 = 13-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 60904

a cytidine in tRNA + S-adenosyl-L-methionine = an N(3)-methylcytidine in tRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 60908

cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine = N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 60912

a cytidine in mRNA + S-adenosyl-L-methionine = an N(3)-methylcytidine in mRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 60916

an N(3)-methylcytidine in mRNA + 2-oxoglutarate + O2 = a cytidine in mRNA + formaldehyde + succinate + CO2

Left to rightBalance undeterminableRhea 60920

N(6)-methyl-L-lysyl-[protein] + 2-oxoglutarate + O2 = L-lysyl-[protein] + formaldehyde + succinate + CO2

Left to rightBalance undeterminableRhea 60924

(9Z)-octadecenoate + reduced [NADPH--hemoprotein reductase] + O2 = 17-hydroxy-(9Z)-octadecenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 60928

(9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2 = 17-hydroxy-(9Z,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 60932

an (omega-1)-ethyl fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = an (omega-1)-hydroxy-long-chain fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 60936

(9Z)-hexadecenoate + reduced [NADPH--hemoprotein reductase] + O2 = (9Z)-16-hydroxyhexadec-9-enoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 60940

quercetin + S-adenosyl-L-methionine = isorhamnetin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 60944

(S)-eriodictyol + S-adenosyl-L-methionine = (S)-homoeriodictyol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 60948

(E)-5-hydroxyferulate + S-adenosyl-L-methionine = (E)-sinapate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 60952

17-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose = (9Z)-17-hydroxyoctadec-9-enoate 17-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 60956

18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose = (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 60960

(9Z)-17-hydroxyoctadec-9-enoate 17-O-beta-D-glucoside + UDP-alpha-D-glucose = (9Z)-17-hydroxyoctadec-9-enoate 17-O-sophoroside + UDP + H(+)

Direction not assertedBalancedRhea 60964

16-hydroxyhexadecanoate + UDP-alpha-D-glucose = 16-hydroxyhexadecanoate 16-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 60968

hexan-1-ol + NAD(+) = hexanal + NADH + H(+)

ReversibleBalancedRhea 60972

(E)-4-hydroxynon-2-en-1-ol + NAD(+) = (E)-4-hydroxynon-2-enal + NADH + H(+)

Right to leftBalancedRhea 60976

12-hydroxydodecanoate + NAD(+) = 12-oxododecanoate + NADH + H(+)

Left to rightBalancedRhea 60980

16-hydroxyhexadecanoate + NAD(+) = 16-oxohexadecanoate + NADH + H(+)

Left to rightBalancedRhea 60984

(E)-hex-2-en-1-ol + NAD(+) = (E)-hex-2-enal + NADH + H(+)

ReversibleBalancedRhea 60988

a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl phosphate + H(+)

Left to rightBalance undeterminableRhea 60992

L-leucine + O2 + H2O = 4-methyl-2-oxopentanoate + H2O2 + NH4(+)

Direction not assertedBalancedRhea 60996

a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = a 2-acyl-6-(alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl phosphate + H(+)

Left to rightBalance undeterminableRhea 61000

a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl phosphate + H(+)

Left to rightBalance undeterminableRhea 61004

(9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + UDP-alpha-D-glucose = (9Z)-18-hydroxyoctadec-9-enoate 18-O-sophoroside + UDP + H(+)

Direction not assertedBalancedRhea 61008

a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 61012

a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 61016

uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)

Left to rightBalancedRhea 61020

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