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2,401–2,450 of 12,877 reactions from Human-GEM
9,10-hydroxyoctadec-12(Z)-enoate[r] + UDP-glucuronate[r] = 10-hydroxy-octadec-(12Z)-enoate-9-beta-D-glucuronide[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Linoleate metabolismHuman-GEM MAR02464
12(13)-EpOME[c] + H2O[c] = 12,13-hydroxyoctadec-9(z)-enoate[c]
ReversibleBalancedEC 3.3.2.9, 3.3.2.10Linoleate metabolismHuman-GEM MAR02465
12(13)-EpOME[r] + H2O[r] = 12,13-hydroxyoctadec-9(z)-enoate[r]
ReversibleBalancedEC 3.3.2.9, 3.3.2.10Linoleate metabolismHuman-GEM MAR02466
12,13-hydroxyoctadec-9(z)-enoate[c] + UDP-glucuronate[c] = 12-hydroxy-13-O-D-glucuronoside-octadec-(9Z)-enoate[c] + H+[c] + UDP[c]
ReversibleBalancedEC 2.4.1.17Linoleate metabolismHuman-GEM
12,13-hydroxyoctadec-9(z)-enoate[r] + UDP-glucuronate[r] = 12-hydroxy-13-O-D-glucuronoside-octadec-(9Z)-enoate[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Linoleate metabolismHuman-GEM MAR02468
12,13-hydroxyoctadec-9(z)-enoate[c] + UDP-glucuronate[c] = 12-O-D-glucuronoside-13-hydroxyoctadec-(9Z)-enoate[c] + H+[c] + UDP[c]
ReversibleBalancedEC 2.4.1.17Linoleate metabolismHuman-GEM MAR02469
12,13-hydroxyoctadec-9(z)-enoate[r] + UDP-glucuronate[r] = 12-O-D-glucuronoside-13-hydroxyoctadec-(9Z)-enoate[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Linoleate metabolismHuman-GEM MAR02470
L-carnitine[r] + linoleate[c] = L-carnitine[c] + linoleate[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR02471
H+[c] + linolenoyl-CoA[c] + NADPH[c] + O2[c] = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA[c] + 2 H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.19.-Omega-3 fatty acid metabolismHuman-GEM MAR02472
gamma-linolenate[r] + L-carnitine[c] = gamma-linolenate[c] + L-carnitine[r]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR02473
L-carnitine[c] + linolenate[r] = L-carnitine[r] + linolenate[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR02474
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA[c] + H+[c] + malonyl-CoA[c] = 3-keto-eicosa-8,11,14,17-all-cis-tetraenoyl-CoA[c] + CO2[c] + CoA[c]
Left to rightBalancedEC 2.3.1.199Omega-3 fatty acid metabolismHuman-GEM MAR02475
L-carnitine[r] + palmitolate[c] = L-carnitine[c] + palmitolate[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR02476
dihomo-gamma-linolenate[r] + L-carnitine[c] = dihomo-gamma-linolenate[c] + L-carnitine[r]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR02477
3-keto-eicosa-8,11,14,17-all-cis-tetraenoyl-CoA[c] + H+[c] + NADPH[c] = 3(S)-hydroxy-all-cis-8,11,14,17-eicosatetraenoyl-CoA[c] + NADP+[c]
Left to rightBalancedEC 1.1.1.330Omega-3 fatty acid metabolismHuman-GEM MAR02478
gamma-linolenoyl-CoA[c] = gamma-linolenoyl-CoA[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR02479
3(S)-hydroxy-all-cis-8,11,14,17-eicosatetraenoyl-CoA[c] = eicosa-(2E,8Z,11Z,14Z,17Z)-pentaenoyl-CoA[c] + H2O[c]
Left to rightBalancedEC 4.2.1.134Omega-3 fatty acid metabolismHuman-GEM MAR02480
dihomo-gamma-linolenoyl-CoA[c] = dihomo-gamma-linolenoyl-CoA[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR02481
eicosa-(2E,8Z,11Z,14Z,17Z)-pentaenoyl-CoA[c] + H+[c] + NADPH[c] = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.93Omega-3 fatty acid metabolismHuman-GEM MAR02482
SAM[m] + Phosphatidyl-N-Methylethanolamine[m] = 2 H+[m] + SAH[m] + Phosphatidyl-N-Dimethylethanolamine[m]
Left to rightBalance undeterminableEC 2.1.1.17Glycerophospholipid metabolismHuman-GEM MAR02483
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA[c] + H+[c] + NADPH[c] + O2[c] = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA[c] + 2 H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.19.-Omega-3 fatty acid metabolismHuman-GEM MAR02484
SAM[r] + Phosphatidyl-N-Methylethanolamine[r] = 2 H+[r] + SAH[r] + Phosphatidyl-N-Dimethylethanolamine[r]
Left to rightBalance undeterminableEC 2.1.1.17Glycerophospholipid metabolismHuman-GEM MAR02485
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA[c] + H+[c] + malonyl-CoA[c] = 3-oxo-docosa-7,10,13,16,19-all-cis-pentaenoyl-CoA[c] + CO2[c] + CoA[c]
Left to rightBalancedEC 2.3.1.199Omega-3 fatty acid metabolismHuman-GEM MAR02486
H2O[m] + stearoyl-CoA[m] = CoA[m] + H+[m] + stearate[m]
ReversibleBalancedEC 3.1.2.2Fatty acid biosynthesisHuman-GEM MAR02487
H2O[x] + stearoyl-CoA[x] = CoA[x] + H+[x] + stearate[x]
ReversibleBalancedEC 3.1.2.2Fatty acid biosynthesisHuman-GEM MAR02488
3-oxo-docosa-7,10,13,16,19-all-cis-pentaenoyl-CoA[c] + H+[c] + NADPH[c] = 3(S)-hydroxy-docosa-7,10,13,16,19-all-cis-pentaenoyl-CoA[c] + NADP+[c]
Left to rightBalancedEC 1.1.1.330Omega-3 fatty acid metabolismHuman-GEM MAR02489
3(S)-hydroxy-docosa-7,10,13,16,19-all-cis-pentaenoyl-CoA[c] = 2-trans-7,10,13,16,19-all-cis-docosahexaenoyl-CoA[c] + H2O[c]
Left to rightBalancedEC 4.2.1.134Omega-3 fatty acid metabolismHuman-GEM MAR02491
(3S)-3-hydroxylinoleoyl-CoA[c] + NAD+[c] = 3-oxolinoleoyl-CoA[c] + H+[c] + NADH[c]
ReversibleBalancedEC 1.1.1.35Fatty acid oxidationHuman-GEM MAR02492
2-trans-7,10,13,16,19-all-cis-docosahexaenoyl-CoA[c] + H+[c] + NADPH[c] = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.93Omega-3 fatty acid metabolismHuman-GEM MAR02493
eicosanoyl-CoA[e] + H+[e] + malonyl-CoA[e] = 3-oxodocosanoyl-CoA[e] + CO2[e] + CoA[e]
Left to rightBalancedEC 1.4.3.13Fatty acid biosynthesisHuman-GEM MAR02494
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[c] + H+[c] + NADPH[c] + O2[c] = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA[c] + 2 H2O[c] + NADP+[c]
Left to rightBalancedOmega-3 fatty acid metabolismHuman-GEM MAR02495
(2E)-docosenoyl-CoA[n] + H+[n] + NADPH[n] = docosanoyl-CoA[n] + NADP+[n]
ReversibleBalancedFatty acid biosynthesisHuman-GEM MAR02496
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[c] + H+[c] + malonyl-CoA[c] = 3-oxo-all-cis-6,9,12,15,18-tetracosapentaenoyl-CoA[c] + CO2[c] + CoA[c]
Left to rightBalancedEC 2.3.1.199Omega-3 fatty acid metabolismHuman-GEM MAR02497
docosanoyl-CoA[n] + H+[n] + malonyl-CoA[n] = 3-oxotetracosanoyl-CoA[n] + CO2[n] + CoA[n]
Left to rightBalancedFatty acid biosynthesisHuman-GEM MAR02498
3-oxo-all-cis-6,9,12,15,18-tetracosapentaenoyl-CoA[c] + H+[c] + NADPH[c] = 3(S)-hydroxy-tetracosa-9,12,15,18,21-all-cis-pentaenoyl-CoA[c] + NADP+[c]
Left to rightBalancedEC 1.1.1.330Omega-3 fatty acid metabolismHuman-GEM MAR02499
eicosanoyl-CoA[m] + H2O[m] = CoA[m] + eicosanoate[m] + H+[m]
ReversibleBalancedEC 3.1.2.2Fatty acid biosynthesisHuman-GEM MAR02500
3(S)-hydroxy-tetracosa-9,12,15,18,21-all-cis-pentaenoyl-CoA[c] = 2-trans-9,12,15,18,21-all-cis-tetracosahexaenoyl-CoA[c] + H2O[c]
Left to rightBalancedEC 4.2.1.134Omega-3 fatty acid metabolismHuman-GEM MAR02501
eicosanoyl-CoA[x] + H2O[x] = CoA[x] + eicosanoate[x] + H+[x]
ReversibleBalancedEC 3.1.2.2Fatty acid biosynthesisHuman-GEM MAR02502
2-trans-9,12,15,18,21-all-cis-tetracosahexaenoyl-CoA[c] + H+[c] + NADPH[c] = (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.93Omega-3 fatty acid metabolismHuman-GEM MAR02503
docosanoyl-CoA[m] + H2O[m] = behenic acid[m] + CoA[m] + H+[m]
ReversibleBalancedEC 3.1.2.2Fatty acid biosynthesisHuman-GEM MAR02504
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA[c] + H+[c] + NADH[c] + O2[c] = (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA[c] + 2 H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.19.3Omega-3 fatty acid metabolismHuman-GEM MAR02505
docosanoyl-CoA[x] + H2O[x] = behenic acid[x] + CoA[x] + H+[x]
ReversibleBalancedEC 3.1.2.2Fatty acid biosynthesisHuman-GEM MAR02506
H2O[m] + tetracosanoyl-CoA[m] = CoA[m] + H+[m] + lignocerate[m]
ReversibleBalancedEC 3.1.2.2Fatty acid biosynthesisHuman-GEM MAR02507
H2O[x] + tetracosanoyl-CoA[x] = CoA[x] + H+[x] + lignocerate[x]
ReversibleBalancedEC 3.1.2.2Fatty acid biosynthesisHuman-GEM MAR02508
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA[c] = (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA[x]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR02509
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA[x] + FAD[x] = delta2-THA-CoA[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Omega-3 fatty acid metabolismHuman-GEM MAR02510
delta2-THA-CoA[x] + H2O[x] = 3-hydroxy-THA-CoA[x]
Left to rightBalancedEC 4.2.1.17Omega-3 fatty acid metabolismHuman-GEM MAR02511
3-hydroxy-THA-CoA[x] + NAD+[x] = 3-keto-THA-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Omega-3 fatty acid metabolismHuman-GEM MAR02512
3-keto-THA-CoA[x] + CoA[x] = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA[x] + acetyl-CoA[x]
Left to rightBalancedEC 2.3.1.16Omega-3 fatty acid metabolismHuman-GEM MAR02513
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA[c] = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA[x]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR02514